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poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) copolymer

structure in first source

Also Known As:

PEG-PPG-PEG

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Kaplan, Meryem: 1 article (10/2020)
2.	Çalış, Sema: 1 article (10/2020)
3.	Öztürk-Atar, Kıvılcım: 1 article (10/2020)
4.	Chen, Yan: 1 article (10/2016)
5.	Gao, Wei: 1 article (10/2016)
6.	Li, Tonglei: 1 article (10/2016)
7.	Park, Kinam: 1 article (10/2016)
8.	Thompson, David H: 1 article (10/2016)
9.	Alam, Maroof: 1 article (05/2015)
10.	Gupta, Dikshi: 1 article (05/2015)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2020 - "These results showed that the encapsulation of TMX into PEG-PPG-PEG micelles facilitated the cellular uptake, which led to an increased cytotoxicity in MCF-7 cancer cells. " 10/01/2016 - "Testing in tumor-bearing mice showed that PTX-NCs treated with Pluronic® F68 (PEG-PPG-PEG block polymer) significantly enhanced blood circulation of the drug and accumulation in tumor tissue. " 05/15/2015 - "These findings thus define an effective approach for (i) sustained administration of GO-203 in polymeric PLA-(PEG-PPG-PEG) nanoparticles to target MUC1-C in cancer cells and (ii) the potential delivery of other anticancer peptide drugs." 01/01/2008 - "Poly(DL-lactic acid) (PLA)/poly(ethylene glycol)-block-poly (propylene glycol)-block-poly(ethylene glycol) copolymer (PEG-PPG-PEG) nanoparticles loaded with camptothecin (CPT), called CPT-NP, were prepared and examined for particle size change and drug release in phosphate-buffered saline, pH 7.4, (PBS), and drug biodistribution profiles in mice bearing sarcoma 180 solid tumor. "
2.	Sarcoma 180 01/01/2008 - "Poly(DL-lactic acid) (PLA)/poly(ethylene glycol)-block-poly (propylene glycol)-block-poly(ethylene glycol) copolymer (PEG-PPG-PEG) nanoparticles loaded with camptothecin (CPT), called CPT-NP, were prepared and examined for particle size change and drug release in phosphate-buffered saline, pH 7.4, (PBS), and drug biodistribution profiles in mice bearing sarcoma 180 solid tumor. "
3.	Hypothermia 11/20/2023 - "However, at 33 °C and pH 6.0 (hypothermia and pH at the thrombotic site), uPA loses the protective effect and recovers its bioactivity due to PEG dissociation and PEG-PPG-PEG stretching. "
4.	Ischemic Stroke 11/20/2023 - "Thus, PEG-uPA-PEG-PPG-PEG provides promising potential for therapeutic hypothermia in ischemic stroke."

Related Drugs and Biologics

1.	poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) copolymer
2.	Lactic Acid (Lactate)
3.	Polymers
4.	Phosphates (Orthophosphate)
5.	Peptides (Polypeptides)
6.	Micelles
7.	Camptothecin
8.	(arginine)9- cysteinyl- glutaminyl- cysteinyl- arginyl- arginyl- lysyl- asparagine
9.	2- cyclohexylidenhydrazo- 4- phenyl- thiazole

Related Therapies and Procedures

1.	Induced Hypothermia