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(18)F-FB-BBN-RGD

Radiopharmaceutical; FB - fluorobenzene; BBN - bombesin; RGD - arginyl-glycyl-aspartic acid; structure in first source

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Chen, Kai: 1 article (03/2008)
2.	Chen, Xiaoyuan: 1 article (03/2008)
3.	Li, Zi-Bo: 1 article (03/2008)
4.	Ryu, Eun Kyoung: 1 article (03/2008)
5.	Wu, Zhanhong: 1 article (03/2008)

Related Diseases

1.

Neoplasms (Cancer)

03/01/2008 - "The receptor-binding characteristics and tumor-targeting efficacy of (18)F-FB-BBN-RGD were tested in vitro and in vivo. "
03/01/2008 - "The PC-3 tumor uptake of (18)F-FB-BBN-RGD was inhibited only partially in the presence of an excess amount of unlabeled BBN(7-14) or c(RGDyK) but was blocked completely in the presence of both BBN(7-14) and c(RGDyK). "
03/01/2008 - "(18)F-FB-BBN-RGD had significantly higher tumor uptake compared with monomeric RGD and monomeric BBN peptide tracer analogs at all time points examined. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	bombesin (7-14)