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ALGRX-4975

an injectable capsaicin (TRPV1 receptor agonist) formulation for longlasting pain relief

Also Known As:

Adlea

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Kirti, Pulugurtha Bharadwaja: 1 article (01/2016)
2.	Kumar, Dilip: 1 article (01/2016)
3.	Kumar, Sumit: 1 article (01/2016)
4.	Rampuria, Sakshi: 1 article (01/2016)
5.	Reddy, Attipalli R: 1 article (01/2016)
6.	Sharma, Akanksha: 1 article (01/2016)
7.	Gavva, Narender R: 1 article (04/2009)
8.	Wong, Gilbert Y: 1 article (04/2009)
9.	Remadevi, Radhika: 1 article (02/2008)
10.	Szallisi, Arpad: 1 article (02/2008)

Related Diseases

1.	Osteoarthritis 02/01/2008 - "In phase II clinical trials, a single injection of Adlea significantly reduced pain levels in patients following total knee arthroplasty (TKA) or bunionectomy, and reduced pain in patients with osteoarthritis (OA) or Morton's neuroma. " 02/01/2008 - "Anesiva Inc is developing Adlea (ALRGX-4975) - an injectable preparation of capsaicin, a TRPV1 (transient receptor potential vanilloid subfamily 1) receptor agonist - for the potential management of pain associated with osteoarthritis, tendonitiand postsurgical conditions, as well as for neuropathic pain occurring secondary to nerve injury. " 04/01/2009 - "Clinical trial results of TRPV1 agonists such as resiniferatoxin in interstitial cystitis, NGX 4010 in post-herpetic neuralgia, and 4975 (Adlea) in osteoarthritis, bunionectomy, and Morton's neuroma have been reported. "
2.	Morton Neuroma 02/01/2008 - "In phase II clinical trials, a single injection of Adlea significantly reduced pain levels in patients following total knee arthroplasty (TKA) or bunionectomy, and reduced pain in patients with osteoarthritis (OA) or Morton's neuroma. " 04/01/2009 - "Clinical trial results of TRPV1 agonists such as resiniferatoxin in interstitial cystitis, NGX 4010 in post-herpetic neuralgia, and 4975 (Adlea) in osteoarthritis, bunionectomy, and Morton's neuroma have been reported. "
3.	Pain (Aches) 02/01/2008 - "Adlea functions by desensitizing those neurons that conduct a long-lasting, throbbing form of pain. " 02/01/2008 - "In phase II clinical trials, a single injection of Adlea significantly reduced pain levels in patients following total knee arthroplasty (TKA) or bunionectomy, and reduced pain in patients with osteoarthritis (OA) or Morton's neuroma. " 02/01/2008 - "Adlea (ALGRX-4975), an injectable capsaicin (TRPV1 receptor agonist) formulation for longlasting pain relief." 02/01/2008 - "Anesiva Inc is developing Adlea (ALRGX-4975) - an injectable preparation of capsaicin, a TRPV1 (transient receptor potential vanilloid subfamily 1) receptor agonist - for the potential management of pain associated with osteoarthritis, tendonitiand postsurgical conditions, as well as for neuropathic pain occurring secondary to nerve injury. "
4.	Neuralgia (Stump Neuralgia) 02/01/2008 - "Adlea appears to exhibit promise as a new medication in the treatment of conditions of chronic neuropathic pain." 02/01/2008 - "Anesiva Inc is developing Adlea (ALRGX-4975) - an injectable preparation of capsaicin, a TRPV1 (transient receptor potential vanilloid subfamily 1) receptor agonist - for the potential management of pain associated with osteoarthritis, tendonitiand postsurgical conditions, as well as for neuropathic pain occurring secondary to nerve injury. " 04/01/2009 - "Clinical trial results of TRPV1 agonists such as resiniferatoxin in interstitial cystitis, NGX 4010 in post-herpetic neuralgia, and 4975 (Adlea) in osteoarthritis, bunionectomy, and Morton's neuroma have been reported. "
5.	Interstitial Cystitis (Interstitial Cystitis, Chronic) 04/01/2009 - "Clinical trial results of TRPV1 agonists such as resiniferatoxin in interstitial cystitis, NGX 4010 in post-herpetic neuralgia, and 4975 (Adlea) in osteoarthritis, bunionectomy, and Morton's neuroma have been reported. "

Related Drugs and Biologics

1.	Capsaicin (Zostrix)
2.	Chlorophyll
3.	TRPV1 receptor
4.	resiniferatoxin

Related Therapies and Procedures

1.	Knee Replacement Arthroplasty (Total Knee Replacement)
2.	Injections