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HEP-40

low MW chitosan for the management of hypercholesterolemia

Networked: 1 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Macromolecular Substances: 97
- Polymers: 13051
  - Biopolymers: 773
    - Chitin: 898
      - Chitosan: 6494
        HEP-40: 1
Carbohydrates: 22023
- Polysaccharides: 15383
  - Chitin: 898
    - Chitosan: 6494
      - HEP-40: 1

Experts

1.	Jaffer, Shahin: 1 article (09/2007)
2.	Sampalis, John S: 1 article (09/2007)

Related Diseases

1.

Hypercholesterolemia

09/01/2007 - "Efficacy and safety of chitosan HEP-40 in the management of hypercholesterolemia: a randomized, multicenter, placebo-controlled trial."
09/01/2007 - "To compare the efficacy of a 12-week treatment regimen with HEP-40 low-molecular weight chitosan given at daily doses of 1,200 mg, 1,600 mg, and 2,400 mg in reducing serum low-density lipoprotein cholesterol (LDL-C) in patients with low-to-moderate hypercholesterolemia. "
09/01/2007 - "HEP-40 low-molecular weight chitosan, although not as effective as statins, is efficacious and safe in lowering LDL-C concentrations in treatment-naive patients with low-to-moderate hypercholesterolemia."

Related Drugs and Biologics

1.	Chitosan
2.	LDL Cholesterol
3.	oxidized low density lipoprotein
4.	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)