|1.||Chung, Kyu Hyuck: 1 article (01/2015)|
|2.||Baeck, Seungkyung: 1 article (01/2015)|
|3.||Kim, Jihyun: 1 article (01/2015)|
|4.||In, Sanghwan: 1 article (01/2015)|
|5.||Lee, Sooyeun: 1 article (01/2015)|
|6.||Choi, Boyeon: 1 article (01/2015)|
|7.||Oh, Seung Min: 1 article (01/2015)|
|8.||Ryu, K H: 1 article (02/2010)|
|9.||Choi, Y H: 1 article (02/2010)|
|10.||Lee, M G: 1 article (02/2010)|
12/01/2009 - "Mirodenafil, a phosphodiesterase 5 inhibitor reported to be effective in the treatment of erectile dysfunction, is metabolized by cytochrome P450 (CYP) 3A4 to the active metabolite N-dehydroxyethyl mirodenafil. "
01/26/2015 - "In the present study, an LC-MS/MS method was developed for the simultaneous determination in hair of five erectile dysfunction drugs having a high risk for abuse (mirodenafil, sildenafil, tadalafil, udenafil and vardenafil) and their selected metabolites (SK3541, desmethylsildenafil, DA8164 and desethylvardenafil). "
02/01/2010 - "The area under the curve (AUC) of mirodenafil after intravenous administration in diabetes mellitus induced by streptozotocin (DMIS) rats was significantly smaller (by 28.0 %) than the control value, and the AUC(SK3541)/AUC(mirodenafil) ratio was significantly greater (by 130 %) in DMIS rats. "
02/01/2010 - "Pharmacokinetics of mirodenafil and its two metabolites, SK3541 and SK3544, after intravenous and oral administration of mirodenafil to streptozotocin-induced diabetes mellitus rats."
|2.||Type 5 Cyclic Nucleotide Phosphodiesterases
|4.||Cytochrome P-450 Enzyme System (Cytochrome P450)
|9.||2- (4- (3- (5- ethyl- 7- n- propyl- 3,5- dihydro- 4H- pyrrolo(3,2- d)pyrimidin- 4- onyl)- 4- n- propoxyphenyl)sulfonylpiperazin- 1- yl)ethyl hydrogen sulfate