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N- methyl- N- (3- ((2- (2- oxo- 2,3- dihydro- 1H- indol- 5- ylamino)- 5- trifluoromethyl- pyrimidin- 4- ylamino)- methyl)- pyridin- 2- yl)- methanesulfonamide

inhibits FAK phosphorylation in vivo in a dose-dependent fashion; structure in first source
Also Known As:
PF-562,271
Networked: 10 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Lamas, Santiago: 2 articles (12/2012 - 05/2012)
2. García-Fernández, Rosa Ana: 2 articles (12/2012 - 05/2012)
3. Lagares, David: 2 articles (12/2012 - 05/2012)
4. Busnadiego, Oscar: 2 articles (12/2012 - 05/2012)
5. Rodríguez-Pascual, Fernando: 2 articles (12/2012 - 05/2012)
6. Slack-Davis, Jill K: 2 articles (11/2011 - 08/2009)
7. Parsons, J Thomas: 2 articles (11/2011 - 08/2009)
8. Andresen, Catharine J: 2 articles (05/2009 - 05/2008)
9. Bagi, Cedo M: 2 articles (05/2009 - 05/2008)
10. Skatchkov, Serguei N: 1 article (01/2015)

Related Diseases

1. Neoplasms (Cancer)
2. Neoplasm Metastasis (Metastasis)
3. Fibrosis (Cirrhosis)
4. Neuroendocrine Carcinoma
5. Prostatic Neoplasms (Prostate Cancer)

Related Drugs and Biologics

1. sunitinib (Sutent)
2. Focal Adhesion Protein-Tyrosine Kinases
3. Small Interfering RNA (siRNA)
4. Collagen
5. Luciferases
6. Bleomycin (Blenoxane)
7. Tumor Viral Antigens (Large T Antigen)
8. 6- (4- (3- (methylsulfonyl)benzylamino)- 5- (trifluoromethyl)pyrimidin- 2- ylamino)- 3,4- dihydroquinolin- 2(1H)- one
9. gemcitabine

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Oral Administration