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Ac- Arg- (Cys- Met- Ava- Arg- Val- Tyr- Ava- Cys)- NH2

Ava -aminovalyl; melanin-concentrating hormone receptor antagonist

Also Known As:

PMC-3881-PI

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Ac-Arg-(Cys-Met-Ava-Arg-Val-Tyr-Ava-Cys)-NH2: 2

Experts

1.	Guo, Feifei: 2 articles (12/2017 - 02/2017)
2.	Sun, Xiangrong: 2 articles (12/2017 - 02/2017)
3.	Xu, Luo: 2 articles (12/2017 - 02/2017)
4.	Luan, Xiao: 1 article (12/2017)
5.	Ma, Li: 1 article (12/2017)
6.	Wang, Cheng: 1 article (12/2017)
7.	Zhang, Di: 1 article (12/2017)
8.	Gao, Shengli: 1 article (02/2017)
9.	Gong, Yanling: 1 article (02/2017)
10.	Pang, Mingjie: 1 article (02/2017)

Related Diseases

1.

AIDS-Related Complex (ARC)

02/01/2017 - "Nesfatin-1 antibody or PMC-3881-PI pretreatment to LHA had no effect on Arc stimulation-induced gastric motility, but these pretreatments did alter Arc stimulation-induced effects on gastric secretion. "
12/01/2017 - "In addition, microinjection of MCH and its receptor antagonist PMC-3881-PI into the ARC affected the role of orexin-A in the ARC, indicating a possible involvement of the MCH pathway in the orexin-A role. "
02/01/2017 - "The results revealed that administration of nesfatin-1 to the LHA or electric stimulation of the Arc could alter the neuronal activity of melanin-concentrating hormone (MCH)-responsive, GD-responsive neurons in LHA, which could be blocked by pretreatment with MCH receptor-1 antagonist PMC-3881-PI or weakened by pretreatment of a nesfatin-1 antibody in LHA. "

Related Drugs and Biologics

1.	Orexins
2.	melanin-concentrating hormone (melanin concentrating hormone)