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GS-9148

anti-HiV; structure in first source

Also Known As:

(5-(6-amino-purin-9-yl)-4-fluoro-2,5-dihydro-furan-2-yloxymethyl)phosphonic acid

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Guanosine: 1156
        GS-9148: 1
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Guanosine: 1156
      - GS-9148: 1
  - Ribonucleosides: 49
    - Guanosine: 1156
      - GS-9148: 1

Experts

1.	Boojamra, Constantine G: 1 article (02/2008)
2.	Carey, Anne: 1 article (02/2008)
3.	Chen, James: 1 article (02/2008)
4.	Cihlar, Tomas: 1 article (02/2008)
5.	Douglas, Janet L: 1 article (02/2008)
6.	Gao, Ying: 1 article (02/2008)
7.	Grant, Deborah: 1 article (02/2008)
8.	Hui, Hon: 1 article (02/2008)
9.	Laflamme, Genevieve: 1 article (02/2008)
10.	Lin, Kuei-Ying: 1 article (02/2008)

Related Diseases

1.	Body Weight (Weight, Body) 02/01/2008 - "Oral administration of GS-9131 to beagle dogs at a dose of 3 mg/kg of body weight resulted in high and persistent levels of GS-9148 diphosphate in peripheral blood mononuclear cells (with a maximum intracellular concentration of >9 microM and a half-life of >24 h). "

Related Drugs and Biologics

1.	Diphosphates (Pyrophosphates)
2.	GS-9131

Related Therapies and Procedures

1.	Oral Administration