HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

CpG ODN 2216

TLR9 receptor agonist; base sequence in first source

Also Known As:

CpG-ODN-2216

Networked: 4 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Polynucleotides: 218
    - Oligonucleotides: 5145
      - Oligodeoxyribonucleotides: 2217
        CpG ODN 2216: 4
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Pattern Recognition Receptors: 3733
        Toll-Like Receptors: 8851
        Toll-Like Receptor 9: 688
        CpG ODN 2216: 4
  - DNA-Binding Proteins: 2009
    - Toll-Like Receptor 9: 688
      - CpG ODN 2216: 4

Experts

1.	Bansal, Reema: 1 article (08/2018)
2.	Gupta, Amod: 1 article (08/2018)
3.	Gupta, Vishali: 1 article (08/2018)
4.	Sachdeva, Naresh: 1 article (08/2018)
5.	Sharma, Kusum: 1 article (08/2018)
6.	Sharma, Ravi Kumar: 1 article (08/2018)
7.	Coester, Conrad: 1 article (06/2012)
8.	Fuchs, Sebastian: 1 article (06/2012)
9.	Gehlen, Heidrun: 1 article (06/2012)
10.	Klier, John: 1 article (06/2012)

Related Diseases

1.	Leukemia 08/01/2009 - "PBMNCs obtained from leukemia patients in remission were incubated with CpG ODN 2216. " 08/01/2009 - "The aim of this study was to investigate the activation ability of CpG oligodeoxynucleotide (CpG ODN) 2216 on the peripheral blood mononuclear cells (PBMNCs) from leukemia patients in remission and the killing effect of activated PBMNCs on K562 cells. "
2.	Airway Obstruction (Choking) 06/01/2012 - "In this study, an aerosol formulation of biodegradable, biocompatible and nontoxic gelatin nanoparticle-bound CpG-ODN 2216 was used to treat equine recurrent airway obstruction in a clinical study. "
3.	Uveitis 08/01/2018 - "Cells were collected from vitreous cassettes and peripheral blood of 8 tubercular uveitis and 5 control subjects, undergoing vitrectomy and analyzed by flow cytometry for cellular composition, activation status, proinflammatory cytokine expression, and uptake of TLR9 ligand, CpG ODN 2216. "
4.	Necrosis 05/01/2004 - "The present work demonstrated that the CpG oligonucleotides (CpG-ODN) 2216, D32 and D19 induce high amounts of interferon-alpha (IFN-alpha), tumour-necrosis factor-alpha (TNF-alpha) and interleukin (IL)-12 in porcine peripheral blood mononuclear cells (PBMCs). "

Related Drugs and Biologics

1.	Oligodeoxyribonucleotides
2.	Gelatin
3.	Aerosols
4.	Interferon-alpha (Interferon Alfa)
5.	Cytokines
6.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
7.	Oligonucleotides
8.	Ligands
9.	Interleukins

Related Therapies and Procedures

1.	Vitrectomy