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Bay w 9798

a dihydropyridine structurally related to nifedipine with no calcium channel-blocking properties, inhibits tumour necrosis factor-alpha-induced vascular cell adhesion molecule-1 expression in endothelial cells by suppressing reactive oxygen species generation; structure in first source
Also Known As:
1,2,6-trimethyl-4-(4-trifluoromethylphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester
Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Matsui, T: 1 article (11/2007)
2. Inoue, H: 1 article (11/2007)
3. Yamagishi, S: 1 article (11/2007)
4. Nakamura, K: 1 article (11/2007)
5. Wagner, A H: 1 article (03/2000)
6. Wachter, R: 1 article (03/2000)
7. Cattaruzza, M: 1 article (03/2000)
8. Hecker, M: 1 article (03/2000)

Related Diseases

1. Atherosclerosis
2. Necrosis

Related Drugs and Biologics

1. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
2. Nifedipine (Adalat)
3. Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)
4. Calcium
5. 1,4-dihydropyridine (dihydropyridine)
6. Interleukin-1beta (Interleukin 1 beta)
7. Nitric Oxide Synthase (NO Synthase)
8. Reactive Oxygen Species (Oxygen Radicals)
9. Calcium Channels (Calcium Channel)