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calycosin-7-O-beta-D-glucoside

from Radix Astragali
Also Known As:
ononin
Networked: 34 relevant articles (4 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Dong, Lin: 2 articles (11/2018 - 01/2017)
2. Fu, Xueyan: 2 articles (11/2018 - 01/2017)
3. Yin, Lei: 2 articles (11/2018 - 01/2017)
4. Maciejewska-Turska, Magdalena: 1 article (06/2022)
5. Makuch-Kocka, Anna: 1 article (06/2022)
6. Plech, Tomasz: 1 article (06/2022)
7. Zgórka, Grażyna: 1 article (06/2022)
8. Han, Jing: 1 article (06/2022)
9. Liu, Tianqiang: 1 article (06/2022)
10. Qu, Shenye: 1 article (06/2022)

Related Diseases

1. Inflammation (Inflammations)
2. Osteosarcoma (Osteogenic Sarcoma)
3. Hypoxia (Hypoxemia)
01/01/2017 - "By using a feedback system control scheme, the best combination of formononetin, ononin, calycosin, and calycosin-7-O-β-d-glucoside derived from Astragali Radix was shown to activate a hypoxia response element, a regulator for erythropoietin (EPO) transcription, in kidney fibroblast. "
11/01/2018 - "Using the anti-inflammatory, anti-oxidation and anti-anoxic activities to screen characteristic components of RA, the calycosin-7-O-β-d-glucoside (CG), ononin, astragaloside IV, astragaloside II, calycosin and astrageloside I significantly inhibited ear edema in mice, the calycosin and CG had good antioxidant activity and the astragaloside I had a significant anti-hypoxia activity. "
09/15/2023 - "MTT assays showed that daidzein, daidzin, puerarin, ononin, genistin, formononetin, 3'-hydroxy puerarin, 3'-methoxy puerarin, mirificin, and 3'-methoxy daidzin exerted protective effects on H9c2 cells against hypoxia/reoxygenation injury. "
01/01/2021 - "On the other hand, the protein expressions levels of hypoxia-inducible factor 1α (HIF-1α), mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK), and vascular endothelial growth factor receptor 2 (VEGFR2) were restricted after ononin treatment for 2 days in VEGF-pretreated endothelial cells. "
09/01/2023 - "Amongst the screened flavonoids, formononetin, calycosin, ononin, chrysin, baicalein and apigenin showed robust up regulation of EPO production via enhancement of hypoxia response element (HRE) activity in cultured embryonic stem cells. "
4. Pain (Aches)
5. Osteoarthritis

Related Drugs and Biologics

1. genistin
2. puerarin
3. daidzin
4. daidzein
5. formononetin
6. Glycyrrhizic Acid (Glycyrrhizin)
7. neoisoliquiritin
8. albiflorin
9. Mitogen-Activated Protein Kinases
10. NF-kappa B (NF-kB)

Related Therapies and Procedures

1. Therapeutics