apple polyphenol extract

from unripe apples; contains about 40% condensed tannin, 20% chlorogenic acid, 7% procyanidin B2, 6% catechin, 4% phloridzin, 3% caffeic acid, 3% procyanidin B1, 1% p-coumaric acid, 1% phloretin, 0.5% (+)- catechinhas; has anti-hepatoma activities

Also Known As:

Networked: 8 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Cacciapuoti, Giovanna: 2 articles (01/2020 - 09/2017)
2.	D'Angelo, Stefania: 2 articles (01/2020 - 09/2017)
3.	Porcelli, Marina: 2 articles (01/2020 - 09/2017)
4.	Cammarota, Marcella: 1 article (01/2020)
5.	Caserta, Sergio: 1 article (01/2020)
6.	Ferraro, Rosalia: 1 article (01/2020)
7.	Guido, Stefano: 1 article (01/2020)
8.	Vuoso, Daniela Cristina: 1 article (01/2020)
9.	Hasselwander, Oliver: 1 article (10/2017)
10.	Junnila, Jouni: 1 article (10/2017)

Related Diseases

1.	Cognitive Dysfunction 10/25/2023 - "Although studies have supported the beneficial effects of the ingredients of apple polyphenol extract (APE), a polyphenol mixture being extracted from whole fresh apples, on neurodegenerative diseases, the role of APE in atherosclerosis-related cognitive impairment remains unclear. " 10/25/2023 - "Apple Polyphenol Extract Ameliorates Atherosclerosis and Associated Cognitive Impairment through Alleviating Neuroinflammation by Weakening TLR4 Signaling and NLRP3 Inflammasome in High-Fat/Cholesterol Diet-Fed LDLR-/- Male Mice."
2.	Atherosclerosis 10/25/2023 - "Although studies have supported the beneficial effects of the ingredients of apple polyphenol extract (APE), a polyphenol mixture being extracted from whole fresh apples, on neurodegenerative diseases, the role of APE in atherosclerosis-related cognitive impairment remains unclear. " 10/25/2023 - "Apple Polyphenol Extract Ameliorates Atherosclerosis and Associated Cognitive Impairment through Alleviating Neuroinflammation by Weakening TLR4 Signaling and NLRP3 Inflammasome in High-Fat/Cholesterol Diet-Fed LDLR-/- Male Mice."
3.	Neuroinflammatory Diseases 10/25/2023 - "Apple Polyphenol Extract Ameliorates Atherosclerosis and Associated Cognitive Impairment through Alleviating Neuroinflammation by Weakening TLR4 Signaling and NLRP3 Inflammasome in High-Fat/Cholesterol Diet-Fed LDLR-/- Male Mice."
4.	Neurodegenerative Diseases (Neurodegenerative Disease) 10/25/2023 - "Although studies have supported the beneficial effects of the ingredients of apple polyphenol extract (APE), a polyphenol mixture being extracted from whole fresh apples, on neurodegenerative diseases, the role of APE in atherosclerosis-related cognitive impairment remains unclear. "
5.	Insulin Resistance 01/01/2016 - "Apple polyphenol extract improves insulin sensitivity in vitro and in vivo in animal models of insulin resistance." 01/01/2016 - "The aim of this study was to test the therapeutic potential of an apple polyphenol extract (APE) in an insulin-resistant rat model and to determine the molecular basis of insulin sensitivity action in skeletal muscle cells. "

Related Drugs and Biologics

1.	Inflammasomes
2.	Cholesterol
3.	Polyphenols
4.	Insulin (Novolin)
5.	Catechin (Z 7300)
6.	flavan-3-ol
7.	Prebiotics
8.	Phosphates (Orthophosphate)
9.	Lipoproteins (Lipoprotein)

Related Therapies and Procedures

1.	Chemoprevention