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IEM 1913
a GluR1 AMPA receptor antagonist; structure in first source
Also Known As:
IEM-1913; IEM1913
Networked:
1
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Polyamines: 3918
Diamines: 518
Putrescine: 919
IEM 1913: 1
Biogenic Amines: 992
Biogenic Polyamines: 11
Putrescine: 919
IEM 1913: 1
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Bridged-Ring Compounds: 1
IEM 1913: 1
Polycyclic Compounds: 6
Bridged-Ring Compounds: 1
IEM 1913: 1
Experts
1.
Gmiro, V E
: 1 article (06/2008)
2.
Serdyuk, S E
: 1 article (06/2008)
Related Diseases
1.
Seizures (Absence Seizure)
06/01/2008 - "
Intramuscular injection of IEM-1913 (combined blockade of NMDA and AMPA receptors in the brain) decreased the incidence of pentylenetetrazole-induced clonic and tonic-clonic seizures in rats by 4-8 times.
"
Related Drugs and Biologics
1.
AMPA Receptors (AMPA Receptor)
2.
N-Methylaspartate (NMDA)
3.
Pentylenetetrazole (Metrazol)
Related Therapies and Procedures
1.
Intramuscular Injections