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mercaptoacetyl-Glu-Glu-Glu

structure in first source

Also Known As:

maEEE

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - mercaptoacetyl-Glu-Glu-Glu: 1

Experts

1.	Abrahmsén, Lars: 1 article (11/2007)
2.	Engfeldt, Torun: 1 article (11/2007)
3.	Feldwisch, Joachim: 1 article (11/2007)
4.	Karlström, Amelie Eriksson: 1 article (11/2007)
5.	Orlova, Anna: 1 article (11/2007)
6.	Sandström, Mattias: 1 article (11/2007)
7.	Tolmachev, Vladimir: 1 article (11/2007)
8.	Tran, Thuy: 1 article (11/2007)
9.	Wennborg, Anders: 1 article (11/2007)

Related Diseases

1.

Neoplasms (Cancer)

11/01/2007 - "(99m)Tc-maEEE-Z(HER2:342) showed a receptor-specific tumor uptake of 7.9 +/- 1.0 %IA/g and a tumor-to-blood ratio of 38 at 4 h pi. "
11/01/2007 - "The biodistribution of (99m)Tc-maGEG-Z(HER2:342) and (99m)Tc-maEEE-Z(HER2:342) was compared with (99m)Tc-maGGG-Z(HER2:342) in normal mice, and the tumor targeting properties of (99m)Tc-maEEE-Z(HER2:342) were determined in SKOV-3 xenografted nude mice. "
11/01/2007 - "(99m)Tc-maEEE-Z(HER2:342), an Affibody molecule-based tracer for the detection of HER2 expression in malignant tumors."
11/01/2007 - "Gamma-camera imaging with (99m)Tc-maEEE-Z(HER2:342) could detect HER2-expressing tumors in xenografts already at 1 h pi. "
11/01/2007 - "Increased hydrophilicity, combined with improved stability of the mercaptoacetyl-triglutamyl chelator, resulted in favorable biodistribution, making (99m)Tc-maEEE-Z(HER2:342) a promising tracer for clinical imaging of HER2 overexpression in tumors."

Related Drugs and Biologics

1.	Chelating Agents

Related Therapies and Procedures

1.	Gamma Cameras (Gamma Camera)