HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

2,2- dimethyl- 5- (6- phenylpyridazin- 3- yl)- 5- aza- 2- azoniabicyclo(2.2.1)heptane

A-585539 is the ((1S,4S)-isomer; a nicotinic agonist; structure in first source

Also Known As:

A 585539; A-585539; A585539

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridazines: 11
    - 2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo(2.2.1)heptane: 1
- Bridged-Ring Heterocyclic Compounds
  - Heterocyclic Bridged Bicyclo Compounds
    - 2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo(2.2.1)heptane: 1

Experts

1.	Anderson, David J: 1 article (01/2008)
2.	Bertrand, Daniel: 1 article (01/2008)
3.	Bunnelle, William: 1 article (01/2008)
4.	Du, Jia: 1 article (01/2008)
5.	Gopalakrishnan, Murali: 1 article (01/2008)
6.	Marguerat, Anouk: 1 article (01/2008)
7.	Surber, Bruce: 1 article (01/2008)
8.	Surowy, Carol: 1 article (01/2008)
9.	Tribollet, Eliane: 1 article (01/2008)

Related Diseases

1.

Neurodegenerative Diseases (Neurodegenerative Disease)

01/01/2008 - "In summary, [(3)H]A-585539 was shown to have excellent binding characteristics in rat and human brain and represents the first high-affinity alpha7 agonist radioligand with utility in the characterization of this important nAChR subtype that is targeted toward ameliorating cognitive deficits underlying neuropsychiatric and neurodegenerative disorders."