HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

1,3,4-thiadiazole-2-thione

structure in first source

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - Thiadiazoles: 99
      - 1,3,4-thiadiazole-2-thione: 2
  - Thiones: 70
    - 1,3,4-thiadiazole-2-thione: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - Thiadiazoles: 99
        1,3,4-thiadiazole-2-thione: 2
Inorganic Chemicals: 9
- Thiones: 70
  - 1,3,4-thiadiazole-2-thione: 2

Experts

1.	Abdel-Hafez, Atef A: 2 articles (06/2009 - 11/2007)
2.	Abdel-Hamid, Mohammed K: 2 articles (06/2009 - 11/2007)
3.	El-Koussi, Nawal A: 2 articles (06/2009 - 11/2007)
4.	Mahfouz, Nadia M: 2 articles (06/2009 - 11/2007)
5.	Innocenti, Alessio: 1 article (11/2007)
6.	Supuran, Claudiu T: 1 article (11/2007)

Related Diseases

1.

Neoplasms (Cancer)

06/01/2009 - "Quantitative structure-activity relationship (QSAR) studies on a series of 1,3,4-thiadiazole-2-thione derivatives as tumor-associated carbonic anhydrase IX inhibitors."
11/15/2007 - "A new series of 1,3,4-thiadiazole-2-thione derivatives have been prepared and assayed for the inhibition of three physiologically relevant carbonic anhydrase (CA, EC 4.2.1.1) isozymes, the cytosolic human isozymes I and II, and the transmembrane, tumor-associated hCA IX. Against hCA I the investigated thiones, showed inhibition constants in the range of 2.55-222 microM, against hCA II in the range of 2.0-433 microM, and against hCA IX in the range of 1.25-148 microM. "

Related Drugs and Biologics

1.	Carbonic Anhydrase IX
2.	Thiones
3.	Isoenzymes
4.	Carbonic Anhydrases (Carbonic Anhydrase)