VRT 018858

metabolite of pralnacasan; has neuroprotective activity

Also Known As:

VRT-018858; VRT018858

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Ischemia 10/01/2007 - "VRT-018858 was neuroprotective when delivered at 1 and 3h (42% and 58% neuroprotection, respectively) but not 6h after injury, and protection was sustained 7 days after the induction of ischemia (66% neuroprotection). " 10/01/2007 - "A selective, non-peptide caspase-1 inhibitor, VRT-018858, markedly reduces brain damage induced by transient ischemia in the rat."

1.	Peptides (Polypeptides)
2.	interleukin-1beta-converting enzyme inhibitor