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N-methyl-2-pyridone-5-carboxamide

Also Known As:

met4PY

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Pyridones: 14
      - N-methyl-2-pyridone-5-carboxamide: 7

Experts

1.	Slominska, Ewa M: 3 articles (01/2018 - 02/2002)
2.	Szolkiewicz, Marek: 3 articles (01/2008 - 02/2002)
3.	Slominska, Ewa: 2 articles (01/2011 - 09/2004)
4.	Rutkowski, Bolesław: 2 articles (01/2008 - 09/2004)
5.	Rutkowski, Przemysław: 2 articles (01/2008 - 09/2004)
6.	Smolenski, Ryszard T: 2 articles (09/2004 - 02/2002)
7.	Swierczynski, Julian: 2 articles (09/2004 - 02/2002)
8.	Czajkowski, Mateusz: 1 article (01/2018)
9.	Gawlik-Jakubczak, Teresa: 1 article (01/2018)
10.	Jablonska, Patrycja: 1 article (01/2018)

Related Diseases

1.	Chronic Kidney Failure (Chronic Renal Failure) 01/01/2008 - "Plasma concentration of Met2PY and Met4PY in end-stage renal disease (ESRD) is several-fold higher in comparison with healthy controls. " 02/01/2002 - "Accumulation of plasma N-methyl-2-pyridone-5-carboxamide in patients with chronic renal failure."
2.	Uremia 09/01/2004 - "Last but not least, trying to elucidate the pathomechanism of adenine nucleotide disturbances in uremia, we have found that the concentration of N-methyl-2-pyridone-5-carboxamide (2PY), one of the end products of nicotinamide-adenine dinucleotide degradation, were enhanced in CRF patients to values that are potentially toxic. "
3.	Neoplasms (Cancer) 01/01/2018 - "The association between the stage of cancer and the increase in both, Met2PY and Met4PY levels was observed. "
4.	Insulinoma 01/01/2011 - "We aimed to verify if 1-methylnicotinamide and its metabolite, N-methyl-2-pyridone-5-carboxamide, can protect insulinoma cells from streptozotocin-induced toxicity. " 01/01/2011 - "Effects of 1-methylnicotinamide and its metabolite N-methyl-2-pyridone-5-carboxamide on streptozotocin-induced toxicity in murine insulinoma MIN6 cell line."
5.	Fatigue 05/01/2010 - "Ethyl N2-acetyl-L-argininate and N-methyl-2-pyridone-5-carboxamide (2-PY) (or N-methyl-4-pyridone-3-carboxamide (4-PY)) were down-regulated, leucylproline and pantothenic acid were up-regulated remarkably both in urine of depression and excess fatigue rats. "

Related Drugs and Biologics

1.	N-methylnicotinamide
2.	Biomarkers (Surrogate Marker)
3.	Streptozocin (Streptozotocin)
4.	Pantothenic Acid (Calcium Pantothenate)
5.	Nucleotides
6.	Niacinamide (Nicotinamide)
7.	NAD (NADH)
8.	Adenine Nucleotides
9.	leucylproline
10.	N(1)-methylnicotinamide