mouse FTO protein

bioinformatics analysis shows FTO shares sequence motifs with Fe(II)- & 2-oxoglutarate-dependent oxygenases; recombinant Fto catalyzes the Fe(II)- & 2OG-dependent demethylation of 3-methylthymine in single-stranded DNA; Fto mRNA is most abundant in brain; RefSeq NM_011936

Also Known As:

FTO protein, mouse; FTO (fat mass and obesity associated) protein, mouse; fat mass and obesity associated protein, mouse

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Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Oxygenases: 333
      - Dioxygenases: 495
        AlkB Enzymes: 4
        Alpha-Ketoglutarate-Dependent Dioxygenase FTO: 139
        mouse FTO protein
    - Oxidoreductases Acting on CH-NH Group Donors
      - N-Demethylating Oxidoreductases: 18
        Alpha-Ketoglutarate-Dependent Dioxygenase FTO: 139
        mouse FTO protein
  - DNA Repair Enzymes: 492
    - AlkB Enzymes: 4
      - Alpha-Ketoglutarate-Dependent Dioxygenase FTO: 139
        mouse FTO protein