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C(alpha)-formylglycine

An unusual amino acid residue found at active site of sulfatases. It is created through the conversion of an active site cysteine or serine residue by C(alpha)-formylglycine (FGly)-generating enzyme. Although the term formylglycine has been used in the literature to refer to C(alpha)-formylglycine it is found in most chemical sources as a synonom for N-formyglycine.
Also Known As:
2-amino-3-oxopropanoic acid; 3-oxo-L-alanine; 3-oxoalanine; L-alpha-formylglycine; alpha-formylglycine; (2S)-2-amino-3-oxopropanoic acid
Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Schmidt, Bernhard: 2 articles (10/2003 - 05/2003)
2. Dierks, Thomas: 2 articles (10/2003 - 05/2003)
3. von Figura, Kurt: 2 articles (10/2003 - 05/2003)
4. Roma, G: 1 article (11/2005)
5. Annunziata, I: 1 article (11/2005)
6. Sardiello, M: 1 article (11/2005)
7. Ballabio, A: 1 article (11/2005)
8. Landgrebe, Jobst: 1 article (10/2003)
9. Borissenko, Ljudmila V: 1 article (05/2003)
10. Mariappan, Malaiyalam: 1 article (05/2003)

Related Diseases

1. Multiple Sulfatase Deficiency Disease (Mucosulfatidosis)
2. Lysosomal Storage Diseases (Lysosomal Storage Disease)

Related Drugs and Biologics

1. Sulfatases
2. Cysteine (L-Cysteine)