|1.||Horiguchi, Jun: 17 articles (01/2015 - 10/2007)|
|2.||Kase, Yoshio: 16 articles (05/2015 - 02/2009)|
|3.||Ikarashi, Yasushi: 13 articles (05/2015 - 02/2009)|
|4.||Yamaguchi, Takuji: 10 articles (05/2015 - 02/2009)|
|5.||Kanno, Hitomi: 9 articles (01/2015 - 09/2009)|
|6.||Furuya, Motohide: 9 articles (01/2015 - 01/2008)|
|7.||Miyaoka, Tsuyoshi: 8 articles (01/2015 - 04/2008)|
|8.||Inagaki, Takuji: 8 articles (06/2013 - 10/2007)|
|9.||Sekiguchi, Kyoji: 7 articles (05/2015 - 09/2009)|
|10.||Kawakami, Zenji: 7 articles (01/2015 - 10/2009)|
01/01/2013 - "Yi-gan san is reported to be effective for the treatment of behavioral and psychological symptoms of dementia. "
09/01/2009 - "Yi-Gan-San (YGS) is a Chinese herbal medicine that is effective in treating the behavioral and psychological symptoms of dementia; however, its physiological mechanism remains unclear. "
03/01/2014 - "[Pharmacological study of the amerliorative effects of Yokukansan on memory impairment and the behavioral and psychological symptoms of dementia in AD models]."
06/01/2013 - "Recent studies indicate that TJ-54 may be safe and useful in treating behavioral and psychological symptoms in dementia patients. "
01/01/2013 - "Yokukansan in the treatment of behavioral and psychological symptoms of dementia: a systematic review and meta-analysis of randomized controlled trials."
|2.||Sleep Initiation and Maintenance Disorders (Insomnia)
01/01/2005 - "TJ-54 has been also used as an effective treatment for insomnia and irritability in recent centuries and is considered to have some effects on the excitability of nerves. "
09/01/2009 - "Yokukansan, a traditional Japanese medicine, has been approved by the Ministry of Health, Labour, and Welfare of Japan as a remedy for neurosis, insomnia or night crying and irritability in children. "
11/01/2011 - "Yokukansan (YKS) has been used in Japan as a remedy for neurosis, insomnia, and children with night crying. "
02/01/2008 - "Yokukansan (TJ-54), a herbal medicine, has been used as a cure for insomnia and irritability in children. "
06/01/2002 - "Yoku-kan-san-ka-chimpi-hange (YKCH) is a drug used for insomnia in Japanese traditional herbal medicine. "
01/01/2011 - "Yi-gan san may be an effective and safe therapy to control visual hallucination in patients with CBS and should be further tested in double-blind, placebo-controlled trials. "
05/26/2015 - "The present study was designed to investigate the mechanisms underlying the ameliorative effects of yokukansan on BPSD using animals exhibiting hallucination-like behaviors. "
01/01/2011 - "Yi-gan san for treatment of charles bonnet syndrome (visual hallucination due to vision loss): an open-label study."
05/26/2015 - "This mechanism may underlie the ameliorative effects of yokukansan on hallucination."
05/26/2015 - "Using this animal model, we next examined the effects of yokukansan on drug-induced hallucination-like behaviors. "
|4.||Psychomotor Agitation (Akathisia)
01/01/2012 - "Yi-gan san (YGS, yokukan-san in Japanese) was developed in 1555 by Xue Kai as a remedy for restlessness and agitation in children. "
01/01/2012 - "Yokukansan, one of the Kampo prescriptions, is composed of seven herbaceous plants and was developed in China in the 16th century as a cure for restlessness and agitation in children. "
04/01/2015 - "Yokukansan is a traditional herbal remedy for restlessness and agitation in children, and mother-infant co-administration (MICA) to both the child and the nursing mother is one of the recommended treatment approaches. "
|5.||Schizophrenia (Dementia Praecox)
01/01/2013 - "Adjunctive yokukansan treatment improved cognitive functions in a patient with schizophrenia."
01/01/2015 - "The results of the present study indicate that TJ-54 showed a tendency of being superior to placebo in reduction PANSS scores in treatment-resistant schizophrenia, but the difference was not statistically significant. "
01/01/2015 - "Efficacy and safety of yokukansan in treatment-resistant schizophrenia: a randomized, multicenter, double-blind, placebo-controlled trial."
01/01/2015 - "Efficacy and safety of yokukansan in treatment-resistant schizophrenia: a randomized, double-blind, placebo-controlled trial (a Positive and Negative Syndrome Scale, five-factor analysis)."
01/01/2014 - "There are several open-label clinical studies upholding the possibility of using yokukansan to treat schizophrenia or schizophrenia-like psychosis. "
|3.||1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)
|4.||Antipsychotic Agents (Antipsychotics)
|5.||Messenger RNA (mRNA)
|7.||Histamine (Histamine Dihydrochloride)
|1.||Kampo Medicine (Kampo)
|2.||Activities of Daily Living (ADL)
|4.||Renal Dialysis (Hemodialysis)
|5.||Chinese Traditional Medicine (Traditional Chinese Medicine)