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EC0225

a folate-targeted dual drug conjugate with antitumor activity; basically consists of subparts: folic acid; the hydrophilic peptide spacer, Asp-Asp-Asp-βDpr-Cys; the Vinca alkaloid drug moiety, DAVLBH; the DNA alkylating drug moiety, N7-mercaptoethyl-mitomycin C (N7-me-MMC); structure in first source
Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Dawson, Alicia: 1 article (09/2007)
2. Leamon, Christopher P: 1 article (09/2007)
3. Reddy, Joseph A: 1 article (09/2007)
4. Westrick, Elaine: 1 article (09/2007)
5. Vetzel, Marilynn: 1 article (09/2007)
6. Wang, Yu: 1 article (09/2007)
7. Santhapuram, Hari Krishna: 1 article (09/2007)
8. Dorton, Ryan: 1 article (09/2007)
9. Vlahov, Iontcho R: 1 article (09/2007)

Related Diseases

1. Neoplasms (Cancer)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)