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5,7-dihydroxy-8-nitrochrysin

NOChR markedly inhibited proliferation of SGC-7901 cells in a dose-dependent manner

Also Known As:

NOChR cpd

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        5,7-dihydroxy-8-nitrochrysin: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        5,7-dihydroxy-8-nitrochrysin: 2
Organic Chemicals: 133
- Nitro Compounds: 66
  - 5,7-dihydroxy-8-nitrochrysin: 2

Experts

1.	Cao, Jian-Guo: 2 articles (03/2013 - 11/2010)
2.	Liu, Fei: 2 articles (03/2013 - 11/2010)
3.	Zhao, Xiao-Chun: 2 articles (03/2013 - 11/2010)
4.	Cao, Xiao-Cheng: 1 article (03/2013)
5.	Quan, Mei-Fang: 1 article (03/2013)
6.	Ren, Kai-Qun: 1 article (03/2013)
7.	Tian, Li: 1 article (11/2010)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 03/01/2013 - "Regulation of the FOXO3a/Bim signaling pathway by 5,7-dihydroxy-8-nitrochrysin in MDA-MB-453 breast cancer cells." 03/01/2013 - "We previously demonstrated that 5,7-dihydroxy-8-nitrochrysin (NOC), a novel synthetic chrysin analog, preferentially inhibits HER-2/neu-overexpressing MDA-MB-453 breast cancer cell growth by inducing apoptosis; however, the precise molecular mechanism was unclear. " 11/01/2010 - "Induction of apoptosis by 5,7-dihydroxy-8-nitrochrysin in breast cancer cells: the role of reactive oxygen species and Akt."
2.	Neoplasms (Cancer) 11/01/2010 - "5,7-dihydroxy-8-nitrochrysin (NOC), a novel synthetic chrysin analogue, induces apoptosis in human cancer cells. "

Related Drugs and Biologics

1.	chrysin
2.	Reactive Oxygen Species (Oxygen Radicals)