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O(4)-benzylfolic acid

Also Known As:

O(4)-BFA

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pteridines: 147
      - Pterins: 160
        Folic Acid: 19425
        O(4)-benzylfolic acid: 2

Experts

1.	Balis, Frank M: 1 article (06/2011)
2.	Chuk, Meredith K: 1 article (06/2011)
3.	Cole, Diane E: 1 article (06/2011)
4.	Fox, Elizabeth: 1 article (06/2011)
5.	Loktionova, Natalia A: 1 article (06/2011)
6.	McCully, Cynthia: 1 article (06/2011)
7.	Parker, Robert J: 1 article (06/2011)
8.	Pauly, Gary: 1 article (06/2011)
9.	Pegg, Anthony E: 1 article (06/2011)
10.	Widemann, Brigitte C: 1 article (06/2011)

Related Diseases

1.	Neoplasms (Cancer) 11/01/2007 - "These results indicate that O(4)-BFA has potentially broad use as an inactivator of AGT as its use is not limited to tumors expressing high levels of FR." 06/01/2011 - "The folate analog O(4)-benzylfolic acid (O(4)BF) is an inhibitor of AGT with reported selectivity of the alpha-folate receptor in tumors. "
2.	Brain Neoplasms (Brain Tumor) 11/01/2007 - "The observed IC(50) for O(4)-BFA in brain tumor cell lines ranged from 0.2 to 1.3 microM for cells grown in media containing 2.3 microM folic acid. " 11/01/2007 - "We measured AGT activity in cell extracts from a panel of brain tumor cells exposed to O(4)-BFA. "

Related Drugs and Biologics

1.	Folic Acid (Vitamin M)
2.	Cell Extracts