poly(ethylene glycol)-poly(aspartate hydrazide)

Also Known As:

PEG-p(Asp-Hyd)

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

1.	Phototoxic Dermatitis (Phototoxicity) 11/14/2013 - "The FA-PEG-P(Asp-Hyd)-DHLA-AuNPs-Pheo showed 99.16% cellular uptake and exhibited an excellent phototoxicity compared to free Pheo and FA-unconjugated nanoparticles at pH 6.4." 10/01/2016 - "In particular, an in vitro cell study revealed high intracellular uptake of FA-PEG-P(Asp-Hyd)-DHLA-AuNPs-Verte (about 98.62%) and marked phototoxicity after laser irradiation compared with free Verte. "
2.	Neoplasms (Cancer) 03/01/2010 - "PEG-p(Asp-Hyd-LEV-PTX) micelles and mixed polymeric micelles exert comparable cytotoxicity against SK-OV-3 and MCF-7 cancer cell lines. " 03/01/2010 - "In summary, mixed polymeric micelles based on PEG-p(Asp-Hyd-LEV-PTX) and PEG-p(Asp-Hyd-4AB-PTX) offer prospects for pH-dependent release of PTX, offering a novel prodrug strategy for adjusting its pharmacokinetic and pharmacodynamic properties for cancer therapy. "