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3-iodotyrosine
Also Known As:
3-iodo-L-tyrosine
Networked:
5
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Hormones, Hormone Substitutes, and Hormone Antagonists
Hormones: 80400
Thyroid Hormones: 10782
Monoiodotyrosine: 31
3-iodotyrosine: 5
Amino Acids, Peptides, and Proteins: 1
Amino Acids: 30675
Cyclic Amino Acids: 3
Aromatic Amino Acids: 467
Tyrosine: 10509
Monoiodotyrosine: 31
3-iodotyrosine: 5
Experts
1.
Bis-Humbert, Cristian
: 1 article (01/2018)
2.
Fernández-Espejo, Emilio
: 1 article (01/2018)
Related Diseases
1.
Hyperprolactinemia
01/01/1982 - "
The use of 3-iodo-L-tyrosine to block brain DA synthesis in these studies has provided significant new data relating to prolactin control in hyperprolactinaemic states and indicates that this compound could be a useful clinical tool in the study of human hyperprolactinaemia.
"
2.
Decapitation
04/01/1996 - "
Thirty planaria per dose were exposed to 0 (control), 0.001, 0.01, 0.1, or 1 mM 3-iodo-L-tyrosine (monoiodotyrosine or MIT) in standard test media beginning 24 hr before decapitation and continuing for 13 days.
"
3.
Parkinsonian Disorders (Parkinsonism)
01/01/2018 - "
In conclusion, excess amounts of 3-iodo-l-tyrosine induce Parkinson-like features in cellular, enteric and brain approaches of Parkinsonism in mice.
"
01/01/2018 - "
Excess amounts of 3-iodo-l-tyrosine induce Parkinson-like features in experimental approaches of Parkinsonism.
"
4.
Hypokinesia (Bradykinesia)
01/01/2018 - "
Infusion of 3-iodo-l-tyrosine into the left dorsal striata of mice damages the nigrostriatal system, as revealed through lower striatal tyrosine-hydroxylase density, reduced number of tyrosine-hydroxylase-expressing and striatum-projecting neurons in the left substantia nigra, as well as the emergence of Parkinson-like behavioral deficits such as akinesia, bradykinesia, motor disbalance, and locomotion directional bias.
"
5.
Pheochromocytoma
10/01/1990 - "
Using enzyme purified from a rat pheochromocytoma, we found that tyrosine, alpha-methyl-p-tyrosine, and a 3-iodotyrosine protected the phosphorylated enzyme against the inactivation produced by tetrahydrobiopterin.
"
Related Drugs and Biologics
1.
Prolactin
2.
Tyrosine (L-Tyrosine)
3.
Enzymes
4.
alpha-Methyltyrosine (Metirosine)
5.
Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)
6.
Tryptophan (L-Tryptophan)
7.
Sodium Dodecyl Sulfate (Sodium Lauryl Sulfate)
8.
Phenylthiourea (Phenylthiocarbamide)
9.
Phenylalanine Hydroxylase (Phenylalanine 4 Monooxygenase)
10.
Fenclonine (p-Chlorophenylalanine)