HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

pyridine-2-carboxaldehyde

structure in first source

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Aldehydes: 2153
  - pyridine-2-carboxaldehyde: 6
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - pyridine-2-carboxaldehyde: 6

Experts

1.	Hueso-Ureña, Francisco: 2 articles (01/2020 - 01/2018)
2.	Illán-Cabeza, Nuria A: 2 articles (01/2020 - 01/2018)
3.	Jiménez-Pulido, Sonia B: 2 articles (01/2020 - 01/2018)
4.	Martínez-Martos, José M: 2 articles (01/2020 - 01/2018)
5.	Moreno-Carretero, Miguel N: 2 articles (01/2020 - 01/2018)
6.	Ramírez-Expósito, María J: 2 articles (01/2020 - 01/2018)
7.	Sánchez-Sánchez, Purificación: 1 article (01/2018)
8.	Bourkoula, Athanasia: 1 article (10/2009)
9.	Livaniou, Evangelia: 1 article (10/2009)
10.	Papadopoulos, Apostolos: 1 article (10/2009)

Related Diseases

1.	Neoplasms (Cancer) 01/01/1995 - "Structure-function relationships for a new series of pyridine-2-carboxaldehyde thiosemicarbazones on ribonucleotide reductase activity and tumor cell growth in culture and in vivo." 10/01/2009 - "Aiming at the development of technetium-99m ((99m)Tc) complexes for early detection and staging of EGFR positive tumors, the tyrosine kinase inhibitor 6-amino-4-[(3-bromophenyl)amino]quinazoline was derivatized with pyridine-2-carboxaldehyde to generate the imine 6-(pyridine-2-methylimine)-4-[(3-bromophenyl)amino]quinazoline suitable for reacting with the fac-[(99m)Tc(CO)(3)](+) core as an N,N bidentate ligand. "
2.	Leukemia L1210 01/01/1995 - "The synthesis of a new series of pyridine-2-carboxaldehyde thiosemicarbazones (HCTs) that have amino groups in the 3- and 5-positions has allowed the comparison of the structure/function relationships with regard to inhibition of ribonucleotide reductase activity, L1210 cell growth in culture and L1210 leukemia in vivo. " 10/02/1992 - "Various substituted pyridine-2-carboxaldehyde thiosemicarbazones (12 compounds) have been synthesized and evaluated for antineoplastic activity in mice bearing the L1210 leukemia. "
3.	Triple Negative Breast Neoplasms 01/01/2018 - "Effects on estrogen-dependent and triple negative breast cancer cells growth of Ni(II), Zn(II) and Cd(II) complexes with the Schiff base derived from pyridine-2-carboxaldehyde and 5,6-diamino-1,3-dimethyluracil explored through the renin-angiotensin system (RAS)-regulating aminopeptidases."
4.	Glioma (Gliomas) 01/01/2020 - "Relationship between the antiproliferative properties of Cu(II) complexes with the Schiff base derived from pyridine-2-carboxaldehyde and 5,6-diamino-1,3-dimethyluracil and the redox status mediated by antioxidant defense systems on glioma tumoral cells."
5.	Colonic Neoplasms (Colon Cancer) 04/01/2002 - "In particular, those with pyridine-2-carboxaldehyde and 2,3-butanedione have CD(50) values of 5.5, 1.9-2.0 microg ml(-1), respectively, against leukemic cells, while against colon cancer cells, the values were 3.7 and 2.0 microg ml(-1), respectively. "

Related Drugs and Biologics

1.	Thiosemicarbazones
2.	Schiff Bases (Schiff Base)
3.	Ribonucleotide Reductases (Ribonucleotide Reductase)
4.	Quinazolines
5.	Ligands
6.	Imines
7.	Estrogens (Estrogen)
8.	Diacetyl (Biacetyl)
9.	Antioxidants
10.	Antineoplastic Agents (Antineoplastics)