Thr- Glu- Lys- Lys- Arg- Arg- Glu- Thr- Val- Glu- Arg- Glu- Lys- Glu

Adjuvants, Immunologic; (patent NO.000015/04-2001 of 08.09.01) is a synthetic peptide made of 14 amino acid residues, producing alpha and beta interferon and macrophage activation and suppression of proinflammatory cytokines

Also Known As:

Hepon

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Thr-Glu-Lys-Lys-Arg-Arg-Glu-Thr-Val-Glu-Arg-Glu-Lys-Glu: 3

Experts

1.	Ataullakhanov, R I: 2 articles (10/2020 - 01/2003)
2.	Chulkina, M M: 1 article (10/2020)
3.	Pichugin, A V: 1 article (10/2020)
4.	Bushmina, O N: 1 article (11/2017)
5.	Harchenko, A V: 1 article (11/2017)
6.	Konoplja, A A: 1 article (11/2017)
7.	Konoplja, A I: 1 article (11/2017)
8.	Litvinova, E S: 1 article (11/2017)
9.	Sunyaykina, O A: 1 article (11/2017)
10.	Firsakova, V Iu: 1 article (01/2003)

Related Diseases

1.	Colitis 10/01/2020 - "Pharmaceutical grade synthetic peptide Thr-Glu-Lys-Lys-Arg-Arg-Glu-Thr-Val-Glu-Arg-Glu-Lys-Glu ameliorates DSS-induced murine colitis by reducing the number and pro-inflammatory activity of colon tissue-infiltrating Ly6G+ granulocytes and Ly6C+ monocytes." 10/01/2020 - "A pharmaceutical grade synthetic tetradecapeptide Thr-Glu-Lys-Lys-Arg-Arg-Glu-Thr-Val-Glu-Arg-Glu-Lys-Glu (GEPON) that mimics the ezrin protein hinge region was studied in dextran sodium sulphate-induced murine experimental colitis (DSS colitis). "
2.	Peptic Ulcer (Peptic Ulcers) 01/01/2003 - "[Use of the immunomodulator hepon in the treatment of erosive peptic ulcer lesions]."
3.	Pancreatitis 11/01/2017 - "Administration of a combination of Hepon, Hypoxenum, and Phosphogliv normalized 22.5% of parameters altered change during development of acute destructive pancreatitis under conditions of chronic alcoholization of parameters, corrected towards normal values 42.5% of parameters (35% of parameters remained unchanged). "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Sodium
3.	Proteins (Proteins, Gene)
4.	Immunologic Factors (Immunomodulators)
5.	Dextrans (Dextran)
6.	Phosphogliv
7.	ezrin