(Au(d2pypp)(2))Cl

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2 relevant articles (0 outcomes, 0 trials/studies) found for this Bio-Agent

Description: d2pypp - 1,3-bis(di-2-pyridylphosphino)propane; induces apoptosis in breast cancer cells, has implications for anticancer therapeutics targeted to mitochondria; structure in first source

Bio-Agent Context: Research Results

Inorganic Chemicals: 5

Phosphorus Compounds: 87

Phosphines: 5

(Au(d2pypp)(2))Cl: 2

Organic Chemicals: 40

Organophosphorus Compounds: 126

Phosphines: 5

(Au(d2pypp)(2))Cl: 2

Organometallic Compounds: 5

Organogold Compounds

(Au(d2pypp)(2))Cl: 2

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 11/21/2007 - "The in vitro cytotoxic activity of [Au(d2pypp)(2)]Cl was assessed in human normal and cancer breast cells and selective toxicity to the cancer cells found" 10/01/2007 - "We show that this gold complex [Au(d2pypp)(2)]Cl, at submicromolar concentrations, selectively induces apoptosis in breast cancer cells but not in normal breast cells" 10/01/2007 - "We show that [Au(d2pypp)(2)]Cl inhibits the activities of both thioredoxin and thioredoxin reductase and that this effect is more pronounced in the breast cancer cells" Get all the results and reference details, order at left...
2.	Neoplasms (Cancer) 11/21/2007 - "The in vitro cytotoxic activity of [Au(d2pypp)(2)]Cl was assessed in human normal and cancer breast cells and selective toxicity to the cancer cells found" Get all the results and reference details, order at left...
2 Diseases and 2 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Thioredoxin-Disulfide Reductase
2.	Thioredoxins
3.	Gold
3 Drugs and Important Bio-Agents and 1 more articles analyzed in the Research Interface, order at left...

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