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auristatin PYE

structure in first source

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - auristatin PYE: 2
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - auristatin PYE: 2

Experts

1.	Bibby, Michael C: 2 articles (03/2010 - 08/2007)
2.	Cooper, Patricia A: 2 articles (03/2010 - 08/2007)
3.	Shnyder, Steven D: 2 articles (03/2010 - 08/2007)
4.	Pettit, George R: 1 article (03/2010)
5.	Prokopiou, Ekatherine M: 1 article (03/2010)
6.	Millington, Nicola J: 1 article (08/2007)
7.	Pettit, G Robert: 1 article (08/2007)

Related Diseases

1.	Colonic Neoplasms (Colon Cancer) 08/01/2007 - "Herein the mechanism of action and efficacy of a synthetic analogue, auristatin PYE, was investigated in 2 human colon adenocarcinoma models, DLD-1 and COLO 205. " 03/01/2010 - "Here, we evaluated the effect of combining auristatin PYE with cisplatin in an HCT-116 human colon adenocarcinoma xenograft model. "
2.	Neoplasms (Cancer) 08/01/2007 - "These data suggest that auristatin PYE has good potential as an anti-cancer agent."

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