HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

butyroyloxymethyl 4-phenylbutyrate

a 4-phenylbutyrate prodrug with antineoplastic activity; structure in first source

Also Known As:

AN 113; AN-113; AN113 cpd

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phenylbutyrates
      - butyroyloxymethyl 4-phenylbutyrate: 2

Experts

1.	Goto, Ayako: 1 article (12/2018)
2.	Harada, Tomoko: 1 article (12/2018)
3.	Harima, Yuji: 1 article (12/2018)
4.	Hirai, Kaoru: 1 article (12/2018)
5.	Inoue, Koki: 1 article (12/2018)
6.	Iwakura, Yoshihiro: 1 article (12/2018)
7.	Miki, Yusuke: 1 article (12/2018)
8.	Miyawaki, Dai: 1 article (12/2018)
9.	Terakawa, Hiroki: 1 article (12/2018)
10.	Yamauchi, Tsuneo: 1 article (12/2018)

Related Diseases

1.	Glioma (Gliomas) 08/18/2007 - "Enthusiasm is lent to this approach by the ability of AN-113 to efficiently kill glioma cells, its bioavailability and potency when administered orally, its capacity to cross the blood-brain barrier, and its effectiveness in combination with radiation." 08/18/2007 - "The precursor of AN-113, 4-phenylbutyrate has shown promising results in a Phase I study of gliomas, and we hypothesized that AN-113 offers significant advantages over the parent drug. " 08/18/2007 - "AN-113, a novel prodrug of 4-phenylbutyrate with increased anti-neoplastic activity in glioma cell lines."
2.	Anorexia Nervosa 12/01/2018 - "This was a cross-sectional study of 284 treatment-seeking female patients aged 13-45 with EDs [171 anorexia nervosa (AN); 113 BN]. "

Related Drugs and Biologics

1.	4-phenylbutyric acid (Buphenyl)
2.	Prodrugs