|1.||Oberlies, Nicholas H: 5 articles (10/2010 - 05/2005)|
|2.||Kroll, David J: 4 articles (10/2010 - 05/2005)|
|3.||Agarwal, Rajesh: 4 articles (10/2010 - 05/2005)|
|4.||Graf, Tyler N: 3 articles (04/2010 - 05/2005)|
|5.||Deep, Gagan: 2 articles (10/2010 - 07/2007)|
|6.||Nakanishi, Yuka: 2 articles (04/2010 - 05/2005)|
|7.||Wani, Mansukh C: 2 articles (04/2010 - 05/2005)|
|8.||Deep, G: 2 articles (06/2008 - 02/2006)|
|9.||Kroll, D J: 2 articles (06/2008 - 02/2006)|
|10.||Agarwal, R: 2 articles (06/2008 - 02/2006)|
|1.||Prostatic Neoplasms (Prostate Cancer)
05/15/2005 - "Whereas several other more abundant flavonolignans do ultimately influence the same end points at higher exposure concentrations, these findings are suggestive that extracts enriched for isosilybin B, or isosilybin B alone, might possess improved potency in prostate cancer prevention and treatment."
10/01/2010 - "Isosilybin A induces apoptosis in human prostate cancer cells via targeting Akt, NF-κB, and androgen receptor signaling."
07/01/2007 - "Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells."
04/01/2010 - "The isolation and structure elucidation of these two new compounds, which we have termed isosilybin C and isosilybin D due to their structural similarities to isosilybin A and isosilybin B, respectively, afforded a preliminary analysis of structure-activity relationships toward prostate cancer growth, survival, and apoptotic endpoints."
02/16/2006 - "Here, we assessed and compared the anticancer efficacy and associated mechanisms of silymarin and silibinin in human prostate cancer (PCA) PC3 cells; silymarin is comprised of silibinin and its other stereoisomers, including isosilybin A, isosilybin B, silydianin, silychristin and isosilychristin. "
06/26/2008 - "Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway."
07/01/2007 - "Here we have assessed the anticancer efficacy of two pure compounds isosilybin B and isosilybin A, isolated from silymarin, in human prostate carcinoma LNCaP and 22Rv1 cells. "
|3.||Hepatocellular Carcinoma (Hepatoma)
|4.||Androgen Receptors (Androgen Receptor)