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PI103

pyridofuropyrimidine antineoplastic; a potent inhibitor of class I phosphatidylinositide 3-kinases (PI3K); structure in first soruce
Also Known As:
PI 103; PI-103
Networked: 53 relevant articles (10 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Workman, Paul: 7 articles (01/2014 - 06/2007)
2. Clarke, Paul A: 7 articles (01/2014 - 06/2007)
3. Fan, Qi-Wen: 5 articles (01/2012 - 05/2006)
4. Weiss, William A: 5 articles (01/2012 - 05/2006)
5. Shokat, Kevan M: 5 articles (01/2010 - 05/2006)
6. Fulda, Simone: 4 articles (04/2015 - 05/2011)
7. Valenti, Melanie: 4 articles (08/2013 - 06/2007)
8. Raynaud, Florence I: 4 articles (07/2010 - 06/2007)
9. Knight, Zachary A: 4 articles (10/2008 - 05/2006)
10. Leach, Martin O: 3 articles (01/2014 - 07/2010)

Related Diseases

1. Neoplasms (Cancer)
2. Glioma (Gliomas)
3. Leukemia
4. Starvation
5. Sarcoma (Soft Tissue Sarcoma)

Related Drugs and Biologics

1. PI103
2. erlotinib (CP 358,774)
3. Phosphotransferases (Kinase)
4. gefitinib (Iressa)
5. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
6. Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
7. Lactic Acid
8. Pyruvic Acid (Pyruvate)
9. Biological Markers (Surrogate Marker)
10. Epidermal Growth Factor Receptor (EGF Receptor)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Heterologous Transplantation (Xenotransplantation)