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TG101209

a small molecule JAK2-selective kinase inhibitor that potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations; structure in first source
Also Known As:
N-tert-butyl-3-(5-methyl-2-(4-(4-methyl-piperazin-1-yl)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide
Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Lo, M-C: 1 article (12/2013)
2. Zhang, D-E: 1 article (12/2013)
3. Dekelver, R C: 1 article (12/2013)
4. Hickman, J H: 1 article (12/2013)
5. Peterson, L F: 1 article (12/2013)
6. Niewerth, D: 1 article (12/2013)
7. Cong, X: 1 article (12/2013)
8. Yan, M: 1 article (12/2013)
9. Gelse, Kolja: 1 article (09/2012)
10. Distler, Oliver: 1 article (09/2012)

Related Diseases

1. Lung Neoplasms (Lung Cancer)
2. Neoplasms (Cancer)
3. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
4. Polycythemia (Erythrocytosis)
5. Myeloproliferative Disorders (Myeloproliferative Disorder)

Related Drugs and Biologics

1. Protein-Tyrosine Kinases (Tyrosine Kinase)
2. Phosphotransferases (Kinase)
3. Bleomycin (Blenoxane)

Related Therapies and Procedures

1. Radiotherapy
2. Heterologous Transplantation (Xenotransplantation)