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LY2183240

structure in first source

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Barker, Eric L: 1 article (12/2010)
2.	Barrenha, Gustavo D: 1 article (12/2010)
3.	Chester, Julia A: 1 article (12/2010)
4.	Mlinac, Nate S: 1 article (12/2010)
5.	Powers, Matthew S: 1 article (12/2010)
6.	Di Marzo, V: 1 article (11/2008)
7.	Ligresti, A: 1 article (11/2008)
8.	Luongo, L: 1 article (11/2008)
9.	Maione, S: 1 article (11/2008)
10.	Marabese, I: 1 article (11/2008)

Related Diseases

1.	Alcoholism (Alcohol Abuse) 12/01/2010 - "The present study assessed the effects of a novel endocannabinoid uptake inhibitor, LY2183240, on anxiety- and alcohol-seeking behaviors in a unique animal model that may represent increased genetic risk to develop co-morbid anxiety and alcohol-use disorders in humans. " 12/01/2010 - "LY2183240 may be an effective pharmacotherapy for individuals with anxiety disorders, such as post-traumatic stress disorder, but may not be appropriate for individuals with co-morbid anxiety and alcohol-use disorders."
2.	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 12/01/2010 - "LY2183240 may be an effective pharmacotherapy for individuals with anxiety disorders, such as post-traumatic stress disorder, but may not be appropriate for individuals with co-morbid anxiety and alcohol-use disorders."
3.	Pancreatic Neoplasms (Pancreatic Cancer) 03/07/2023 - "Conclusions: 5-Fluoro NPB-22, FUB-NPB-22, and LY2183240 represent new leads against prostate and pancreatic cancer cells in addition to the previously reported compounds, HU-331, (±)5-epi-CP55,940, and PTI-2. "
4.	Pain (Aches) 11/01/2008 - "We tested, in a model of inflammatory pain induced in mice by formalin, five chemically similar inhibitors: (i) OMDM119 and OMDM122, two potent carbamoyl tetrazole FAAH inhibitors with no effect on anandamide uptake; (ii) LY2183240, a carbamoyl tetrazole with activity as both FAAH and uptake inhibitor; (iii) OMDM132, a non-carbamoyl tetrazole with activity only as uptake inhibitor and iv) OMDM133, a non-carbamoyl tetrazole with no activity at either FAAH or uptake. "
5.	Anxiety Disorders (Anxiety Disorder) 12/01/2010 - "LY2183240 may be an effective pharmacotherapy for individuals with anxiety disorders, such as post-traumatic stress disorder, but may not be appropriate for individuals with co-morbid anxiety and alcohol-use disorders."

Related Drugs and Biologics

1.	Endocannabinoids
2.	Formaldehyde (Formol)
3.	anandamide (arachidonylethanolamide)
4.	cannabidiol hydroxyquinone (HU331)
5.	1H-tetrazole (tetrazole)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)