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enhydrin

from Tetragonotheca sp. (Asteraceae); structure in first source

Networked: 6 relevant articles (2 outcomes, 2 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - enhydrin: 6

Experts

1.	Genta, S B: 1 article (06/2017)
2.	Habib, N C: 1 article (06/2017)
3.	Honoré, S M: 1 article (06/2017)
4.	Serra-Barcellona, C: 1 article (06/2017)
5.	Sánchez, S S: 1 article (06/2017)
6.	Catalán, C: 1 article (01/2013)
7.	Cazorla, S I: 1 article (01/2013)
8.	Frank, F M: 1 article (01/2013)
9.	Grau, A: 1 article (01/2013)
10.	Malchiodi, E L: 1 article (01/2013)

Related Diseases

1.	Body Weight (Weight, Body) 06/01/2017 - "In vivo experiments showed a rapid decrease in the hyperglycemic peak after sucrose load (2 g/kg body weight) in normal rats treated with the 10% decoction (140 mg/kg) and enhydrin (0.8 mg/kg). " 04/29/2010 - "Additionally, enhydrin, the major sesquiterpene lactone of yacon leaves, was also effective to reduce post-prandial glucose and useful in the treatment of diabetic animals (minimum dose: 0.8mg/kg body weight). "
2.	Pain (Aches) 10/01/2004 - "These findings suggest that parthenolide and enhydrin from these plant sources may be useful in the treatment of inflammatory pain."
3.	Neoplasms (Cancer) 06/01/2007 - "Enhydrin, tetraludin A and repandins A, B, D and E inhibited tumor cell growth and induced cell cycle arrest and apoptosis. " 06/01/2007 - "The aim of this study was to investigate the effects of sesquiterpenes isolated from Asteraceae, namely melampolides (enhydrin, tetraludin A) and repandolides (repandins A, B, D and E) on the activation of NF-kappaB, cell growth of cancer cells, cell cycle progression and apoptosis. "
4.	Uterine Cervical Neoplasms (Cancer of the Cervix) 10/01/2011 - "The present study investigated the cytotoxicity of enhydrin (1), uvedalin (2) and sonchifolin (3) in cervical cancer cells. "
5.	Chagas Disease (American Trypanosomiasis) 01/01/2013 - "According to these results, enhydrin and uvedalin might have potentials as agents against Chagas disease and could serve as lead molecules to develop new drugs. "

Related Drugs and Biologics

1.	Sesquiterpenes
2.	Lactones
3.	Glucose (Dextrose)
4.	parthenolide
5.	uvedalin
6.	NF-kappa B (NF-kB)
7.	tetraludin A
8.	Sucrose (Saccharose)
9.	Glucosidases