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poly(L- lysine)- b- poly(L- lactide)- b- dendritic poly(L-lysine)

structure in first source

Also Known As:

D2-LLA15-D2

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Cao, Amin: 1 article (05/2007)
2.	Cui, Liang: 1 article (05/2007)
3.	Fang, Qiang: 1 article (05/2007)
4.	Jia, Lin: 1 article (05/2007)
5.	Li, Qiaobo: 1 article (05/2007)
6.	Li, Yang: 1 article (05/2007)
7.	Xu, Yuhong: 1 article (05/2007)

Related Diseases

1.

Hepatocellular Carcinoma (Hepatoma)

05/01/2007 - "Moreover, the assembled polyplex microparticles of plasmid DNA/polycationic carrier were further analyzed by dynamic light scattering and transmission electron microscopy, indicating their averaged nanoparticle size around 150-200 nm. As for the cytotoxicity of the new D2-LLA15-D2, MTT assays were conducted with a human hepatocellular carcinoma cell line (SMMC-7721), indicating a very low cytotoxicity as compared with commercial linear PLL-23K and PEI-2K, and a DNase I degradation of the assembled polyplex particles was also done in the HBS buffer solution to evaluate their stabilities. "

Related Drugs and Biologics

1.	Solutions
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3.	Deoxyribonuclease I (Nickase)
4.	Buffers