(4-sulfamoylphenylethyl)thioureido fluorescein

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1 relevant articles (0 outcomes, 1 trials/studies) found for this Bio-Agent

Description: structure in first source

Also Known As:

4-SPTU F cpd

Bio-Agent Context: Research Results

Related Diseases

06/28/2006 - "The X-ray crystal structure of the fluorescent antitumor sulfonamide carbonic anhydrase (CA, EC, 4.2.1.1) inhibitor (4-sulfamoylphenylethyl)thioureido fluorescein (1) in complex with the cytosolic isoform hCA II is reported, together with a modeling study of the adduct of 1 with the tumor-associated isoform hCA IX. Its binding to hCA II is similar to that of other benzesulfonamides, with the ionized sulfonamide coordinated to the Zn2+ ion within the enzyme active site, and also participating in a network of hydrogen bonds with residues Thr199 and Glu106"
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1 Diseases and 1 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Hydrogen
2.	Carbonic Anhydrases (Carbonic Anhydrase)
2 Drugs and Important Bio-Agents and 1 more articles analyzed in the Research Interface, order at left...

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