lobetyolin

07/04/2022 - "Recent studies have shown that lobetyolin (LBT) is one of the main bioactive compounds of traditional Chinese medicines and it exhibits anticancer activity in several types of cancer. "
10/01/2023 - "Overall, lobetyolin exerts anti-cancer effects by repressing cell proliferation and inducing cell apoptosis via downregulation of ASCT2 in GC."
10/01/2023 - "Lobetyolin effectively restrained the growth of tumors in vivo. "
10/01/2023 - "Lobetyolin, as a bioactive ingredient extracted from Codonopsis pilosula (Franch.) Nannf., has been reported to exert anti-tumor effects in several cancer types. "
12/01/2021 - "SLC1A5 knockdown attenuated the anti-cancer effect of lobetyolin. "

01/01/2020 - "The purpose of the present study was to evaluate the anti-cancer property of Lobetyolin on colorectal cancer and explore its potential mechanism. "

12/01/2021 - "The results showed that lobetyolin inhibited the proliferation of both MDA-MB-231 and MDA-MB-468 breast cancer cells. "
12/01/2021 - "Lobetyolin was incubated with MDA-MB-231 and MDA-MB-468 breast cancer cells for 24 h. "
12/01/2021 - "Lobetyolin inhibits the proliferation of breast cancer cells via ASCT2 down-regulation-induced apoptosis."
12/01/2021 - "This study aimed to investigate the anti-cancer effect of lobetyolin on breast cancer cells. "
12/01/2021 - "In conclusion, the present work suggested that lobetyolin exerted anti-cancer effect via ASCT2 down-regulation-induced apoptosis in breast cancer cells."

06/01/2010 - "In an ongoing project directed toward the discovery of novel treatments for diabetic complications from traditional herbal medicines, fifteen compounds, apigenin (1), apigenin-7-O-beta-D: -glucopyranoside (2), apigenin-7-O-(6''-O-acetyl)-beta-D: -glucopyranoside (3), luteolin (4), luteolin-7-O-beta-D: -glucopyranoside (5), luteolin-7-O-(6''-O-acetyl)-beta-D: -glucopyranoside (6), isorhamnetin-3-Oneohesperidoside (7), 4-O-caffeoylquinic acid (8), chlorogenic acid methyl ester (9), 4-O-beta-D: -glucopyranosylcaffeic acid (10), lobetyolin (11), cordifolioidyne C (12), isomultiflorenyl acetate (13), beta-sitosterol glucoside (14), and alpha-spinosterol (15), were isolated from an EtOAc-soluble fraction of the flowers of Platycodon grandiflorum (balloonflower; Campanulaceae). "

10/01/2023 - "Lobetyolin inhibits cell proliferation and induces cell apoptosis by downregulating ASCT2 in gastric cancer."