|1.||Chen, Chung-Yi: 4 articles (04/2012 - 07/2007)|
|2.||Chern, Chi-Liang: 2 articles (04/2012 - 07/2007)|
|3.||Yiin, Shuenn-Jiun: 2 articles (04/2012 - 07/2007)|
|4.||Chen, Ching-Hsein: 2 articles (06/2008 - 07/2007)|
|5.||Lin, Shan-Chun: 1 article (04/2012)|
|6.||Wang, Wei-Che: 1 article (04/2012)|
|7.||Hsu, Jue-Liang: 1 article (04/2012)|
|8.||Wang, Hui-Min: 1 article (06/2008)|
|9.||Lo, Yi-Ching: 1 article (06/2008)|
|10.||Wu, Bin-Nan: 1 article (06/2008)|
|1.||Hepatocellular Carcinoma (Hepatoma)
07/01/2007 - "In this study, the effects of isoobtusilactone A, a novel constituent isolated from the leaves of Cinnamomum kotoense, on the proliferation of human hepatoma Hep G2 cells were studied. "
04/04/2012 - "Isoobtusilactone A sensitizes human hepatoma Hep G2 cells to TRAIL-induced apoptosis via ROS and CHOP-mediated up-regulation of DR5."
04/04/2012 - "We have previously shown that isoobtusilactone A (IOA), a potent anticancer agent isolated from Cinnamomum kotoense, induced mitochondria-mediated apoptosis in hepatoma cells. "
07/01/2007 - "Isoobtusilactone A-induced apoptosis in human hepatoma Hep G2 cells is mediated via increased NADPH oxidase-derived reactive oxygen species (ROS) production and the mitochondria-associated apoptotic mechanisms."
|2.||Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
|3.||Breast Neoplasms (Breast Cancer)
08/01/2007 - "This study is the first to investigate the anticancer effect of isoobtusilactone A (IOA) in two human breast cancer cell lines, MCF-7 and MDA-MB-231. "
08/01/2007 - "Isoobtusilactone A induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal-regulating kinase 1 signaling pathway in human breast cancer cells."
|2.||Reactive Oxygen Species (Oxygen Radicals)
|3.||MAP Kinase Kinase Kinase 5
|4.||NADPH Oxidase (NAD(P)H oxidase)