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1-acetonaphthone

Also Known As:

1-acetylnaphthalene

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        1-acetonaphthone: 2
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - 1-acetonaphthone: 2

Related Diseases

1.	Phototoxic Dermatitis (Phototoxicity) 06/01/1987 - "The phototoxicity of 2-acetylnaphthalene, 1-acetylnaphthalene, 1-naphthalenecarboxaldehyde, 9-xanthenone, 9-thioxanthenone, 9-methylanthracene, anthracene, alpha-terthienyl, pyrene and fluoranthene was tested with larvae of Aedes aegypti, Ae. taeniorhynchus and Culex quinquefasciatus. "
2.	Hyperthyroidism 10/01/2023 - "The results of decreased Root Mean Square Fluctuation (RMSF) values via 20-ns molecular dynamics (MD) simulations under 15%, 25%, 35%, and 45% DMSO revealed that mutant M3 had lower flexibility, acquiring a more stable protein structure and contributing to its organic solvents stability than WT. Furthermore, M3 was applied to convert 1-acetylnaphthalene for synthesizing (R)-(+)-1(1-naphthyl)-ethylamine ((R)-NEA), which was an intermediate of Cinacalcet Hydrochloride for the treatment of secondary hyperthyroidism and hypercalcemia. "
3.	Hypercalcemia (Milk Alkali Syndrome) 10/01/2023 - "The results of decreased Root Mean Square Fluctuation (RMSF) values via 20-ns molecular dynamics (MD) simulations under 15%, 25%, 35%, and 45% DMSO revealed that mutant M3 had lower flexibility, acquiring a more stable protein structure and contributing to its organic solvents stability than WT. Furthermore, M3 was applied to convert 1-acetylnaphthalene for synthesizing (R)-(+)-1(1-naphthyl)-ethylamine ((R)-NEA), which was an intermediate of Cinacalcet Hydrochloride for the treatment of secondary hyperthyroidism and hypercalcemia. "

Related Drugs and Biologics

1.	Solvents
2.	Proteins (Proteins, Gene)
3.	Dimethyl Sulfoxide (DMSO)
4.	Cinacalcet (Sensipar)
5.	2-acetylnaphthalene
6.	9-methylanthracene
7.	ethylamine
8.	anthracene
9.	pyrene
10.	alpha-terthienyl (terthiophene)