|1.||Bearss, David: 2 articles (01/2009 - 01/2009)|
|2.||Mahadevan, Daruka: 2 articles (01/2009 - 01/2009)|
|3.||Meng, Alice X: 1 article (10/2011)|
|4.||Zhao, Helen: 1 article (10/2011)|
|5.||Bristow, Robert G: 1 article (10/2011)|
|6.||Luoto, Kaisa R: 1 article (10/2011)|
|7.||Redkar, S: 1 article (04/2011)|
|8.||Dauser, R C: 1 article (04/2011)|
|9.||Blaney, S M: 1 article (04/2011)|
|10.||Baxter, P A: 1 article (04/2011)|
|1.||Prostatic Neoplasms (Prostate Cancer)
01/01/2009 - "MP470 exhibits low microM IC50 in prostate cancer cell lines. "
01/01/2009 - "The efficacy of MP470 or MP470 plus Erlotinib was evaluated in vitro using three prostate cancer cell lines by MTS and apoptosis assays. "
01/01/2009 - "In this study, we evaluate whether MP470, a novel receptor tyrosine kinase inhibitor alone or in combination with Erlotinib has inhibitory effect on prostate cancer in vitro and in vivo. "
01/01/2009 - "MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer."
04/01/2011 - "Although CSF penetration is minimal, MP470 has demonstrated potent activity against cancer cell lines in vitro and in vivo, and further clinical investigation is warranted."
01/01/2009 - "In vivo, the addition of MP470 to radiation resulted in a tumor-growth-delay enhancement ratio of 2.9 over radiation alone and extended survival time. "
01/01/2009 - "A LNCaP mouse xenograft model was also used to determine the tumor growth inhibition by MP470, Erlotinib or the combination treatments. "
10/01/2011 - "Amuvatinib (formerly known as MP470) is a novel receptor tyrosine kinase inhibitor that targets c-KIT and PDGFRα and can sensitize tumor cells to ionizing radiation (IR). "
10/01/2011 - "The receptor tyrosine kinase inhibitor amuvatinib (MP470) sensitizes tumor cells to radio- and chemo-therapies in part by inhibiting homologous recombination."
|3.||Glioblastoma (Glioblastoma Multiforme)
|1.||erlotinib (CP 358,774)
|3.||tyrosine receptor (receptor, tyrosine)
|1.||Heterologous Transplantation (Xenotransplantation)