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alpha1(IV)1263-1277 PA

a triple-helical peptide amphiphile that binds CD44; amino acid sequence in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - alpha1(IV)1263-1277 PA: 1

Experts

1.	Baronas-Lowell, Diane: 1 article (04/2007)
2.	Cudic, Mare: 1 article (04/2007)
3.	Fields, Gregg B: 1 article (04/2007)
4.	Khan, David R: 1 article (04/2007)
5.	Lauer-Fields, Janelle: 1 article (04/2007)
6.	Rezler, Evonne M: 1 article (04/2007)

Related Diseases

1.

Melanoma (Melanoma, Malignant)

04/25/2007 - "When metastatic melanoma cells and fibroblasts were treated with exogeneous alpha1(IV)1263-1277, prior to incubation with alpha1(IV)1263-1277 PA liposomes, to potentially disrupt receptor/liposome interactions, a dose-dependent decrease in the amount of fluorophore delivered was observed. "
04/25/2007 - "A positive correlation was observed for cellular fluorophore delivery by the alpha1(IV)1263-1277 PA liposomes and CD44/CSPG receptor content in metastatic melanoma and fibroblast cell lines. "

Related Drugs and Biologics

1.	Liposomes (Liposome)