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nigerasperone A
a naphtho-gamma-pyrone from a marine alga-derived endophytic fungus Aspergillus niger; structure in first source
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
nigerasperone A: 1
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
nigerasperone A: 1
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrans: 130
Pyrones: 35
nigerasperone A: 1
Experts
1.
Arnold, A Elizabeth
: 1 article (10/2020)
2.
Gunatilaka, A A Leslie
: 1 article (10/2020)
3.
U Ren, Jana M
: 1 article (10/2020)
4.
Wang, Wen-Qiong
: 1 article (10/2020)
5.
Xu, Ya-Ming
: 1 article (10/2020)
6.
Xuan, Li-Jiang
: 1 article (10/2020)
Related Diseases
1.
Prostatic Neoplasms (Prostate Cancer)
10/30/2020 - "
Cytotoxicity assay revealed that nigerasperone A (7) was moderately active against the cancer cell lines PC-3M (human metastatic prostate cancer), NCI-H460 (human non-small cell lung cancer), SF-268 (human CNS glioma), and MCF-7 (human breast cancer), with IC50s ranging from 2.37 to 4.12 μM while other metabolites exhibited no cytotoxic activity up to a concentration of 5.0 μM.
"
2.
Neoplasms (Cancer)
10/30/2020 - "
Cytotoxicity assay revealed that nigerasperone A (7) was moderately active against the cancer cell lines PC-3M (human metastatic prostate cancer), NCI-H460 (human non-small cell lung cancer), SF-268 (human CNS glioma), and MCF-7 (human breast cancer), with IC50s ranging from 2.37 to 4.12 μM while other metabolites exhibited no cytotoxic activity up to a concentration of 5.0 μM.
"
3.
Glioma (Gliomas)
10/30/2020 - "
Cytotoxicity assay revealed that nigerasperone A (7) was moderately active against the cancer cell lines PC-3M (human metastatic prostate cancer), NCI-H460 (human non-small cell lung cancer), SF-268 (human CNS glioma), and MCF-7 (human breast cancer), with IC50s ranging from 2.37 to 4.12 μM while other metabolites exhibited no cytotoxic activity up to a concentration of 5.0 μM.
"
4.
Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/30/2020 - "
Cytotoxicity assay revealed that nigerasperone A (7) was moderately active against the cancer cell lines PC-3M (human metastatic prostate cancer), NCI-H460 (human non-small cell lung cancer), SF-268 (human CNS glioma), and MCF-7 (human breast cancer), with IC50s ranging from 2.37 to 4.12 μM while other metabolites exhibited no cytotoxic activity up to a concentration of 5.0 μM.
"
5.
Breast Neoplasms (Breast Cancer)
10/30/2020 - "
Cytotoxicity assay revealed that nigerasperone A (7) was moderately active against the cancer cell lines PC-3M (human metastatic prostate cancer), NCI-H460 (human non-small cell lung cancer), SF-268 (human CNS glioma), and MCF-7 (human breast cancer), with IC50s ranging from 2.37 to 4.12 μM while other metabolites exhibited no cytotoxic activity up to a concentration of 5.0 μM.
"