|1.||Kumar, Ashok: 3 articles (05/2015 - 11/2011)|
|2.||Shakya, Akhilesh Kumar: 3 articles (01/2014 - 11/2011)|
|3.||Nandakumar, Kutty Selva: 3 articles (01/2014 - 11/2011)|
|4.||Fischer, Itzhak: 3 articles (06/2013 - 05/2009)|
|5.||Lowman, Anthony: 3 articles (06/2013 - 05/2009)|
|6.||Chen, Jun: 2 articles (04/2015 - 07/2014)|
|7.||Holmdahl, Rikard: 2 articles (08/2013 - 11/2011)|
|8.||Vernengo, Jennifer: 2 articles (06/2013 - 12/2011)|
|9.||Jin, Ying: 2 articles (06/2013 - 12/2011)|
|10.||Himes, B Timothy: 2 articles (06/2013 - 12/2011)|
|1.||Wounds and Injuries (Trauma)
11/01/2006 - "The results showed that the rate of cell growth and wound recovery in the hDMSC and gelatin/pNIPAAm/PP-treated group was significantly greater than those in the gelatin/pNIPAAm/PP-treated only group (P < .01). "
03/01/2008 - "The results showed that the rates of cell growth and wound recovery in the hBMSC-treated group were significantly higher than those in the control group, which was only treated with the gelatin/pNIPAAm (p < 0.01). "
11/01/2001 - "All these results suggest that a novel drug-loaded wound dressing has been developed by binding a self-adhesive Eudragit E film with an antibacterial drug-loaded PNIPAAm microgel beads to achieve thermo-responsive, adhesive, absorptive and easy peeling functions."
11/01/2001 - "The water uptake ratio of Eudragit E film containing PNIPAAm microgel beads was found to be temperature-dependent, suggesting that the Eudragit E film containing PNIPAAm microgel beads enabled to absorb the wound fluid. "
04/01/2012 - "These results suggest that PNIPAAm hydrogels containing A-Lys are promising wound dressings due to their ability to promote healing and deliver active antimicrobial drugs to inhibit infection."
07/06/2015 - "However, this PSs-loaded nanosystem became highly phototoxic as it underwent the near-infrared irradiation by using the combined lights of 808 and 680 nm. Upon irradiation, the Tat/HA2 conjugated AuNR@pNIPAAm-Pc elicited an active photodynamic response against the cancer cells, leading to effective cells killing via mitochondria-associated apoptotic pathway. "
04/01/2015 - "Confocal laser scanning microscopy (CLSM) was utilized to demonstrate the enhanced cell uptake of the as prepared nanoparticles and the faster drug release under the NIR irradiation and lower pH. All the results suggest that multifunctional DOX-loaded CS/PNIPAAm@CNT nanocomposite is a promising therapeutic nanocarrier for intracellular drug delivery with great potential for targeted cancer therapy."
07/06/2015 - "This study also demonstrated improved PDT therapeutic efficacy after intravenous administration of Tat/HA2-AuNR@pNIPAAm-Pc and the subsequent lights irradiations in tumor-bearing mice. "
12/24/2014 - "Interestingly, DOX-loaded alginate-g-PNIPAAm micelles showed excellent anti-cancer therapeutic efficacy in a mouse model without any significant side effects. "
12/24/2014 - "Doxorubicin (DOX), a model anti-cancer drug, was efficiently encapsulated in alginate-g-PNIPAAm micelles, and sustained release of DOX from the micelles was achieved at 37 °C in vitro. "
|4.||Body Weight (Weight, Body)
10/01/2005 - "In conclusion, PNIPAAm-co-NVA is well tolerated up to 4000 mg/kg body weight when administered orally. "
10/01/2005 - "A preliminary acute oral toxicity study was performed with one of the polymer (PNIPAAm-co-NVA) at a unique dose of 4000 mg/kg body weight administered to six male and six female mice, to determine the dosage for further evaluation. "
|5.||Dehydration (Water Stress)
08/01/2007 - "Scanning electron microscopy (SEM) revealed that the blended swollen films exhibited a more porous structure at 37 degrees C (>LCST) than at room temperature (<LCST), though their swelling ratios were reduced as temperature increased from room temperature to 37 degrees C because of the dehydration nature of PNIPAAm at temperatures above its LCST. "
10/01/2006 - "We found that the usual aggregation and phase separation of PNIPAAm-SA conjugates that follow the thermally induced collapse and dehydration of PNIPAAm (the lower critical solution temperature (LCST) of PNIPAAm is 32 degrees C in water) is prevented through the shielding action of the PAA block. "
08/10/2015 - "The poly(N-isopropylacrylamide) (PNIPAAm) chain showed an expanded coil conformation below the lower critical solution temperature (LCST) due to hydration, but it changed to a globular form above the LCST due to dehydration. "
01/01/2011 - "Cell sheet technology (CST) is based on the use of poly (N-isopropylacrylamide, PNIPAAm), which can be exhibit reversible hydration and dehydration of its polymer chains in response to temperature changes across the lower critical solution temperature(LCST)of 32°C. "
06/21/2003 - "Through copolymerization/crosslinking in dimethyl sulfoxide (DMSO) at temperature below the melting point of DMSO, we demonstrated a novel poly(N-isopropylacrylamide) (PNIPAAm) hydrogel with regularly oriented micromatrix; the superfast/stable oscillatory hydration-dehydration character of this hydrogel would find wide applications in biomedical field."
|8.||alginic acid (sodium alginate)