2- ((2,6- dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester

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2 relevant articles (0 outcomes, 1 trials/studies) found for this Bio-Agent

Description: an NSAID; structure in first source

Also Known As:

S-diclofenac

Bio-Agent Context: Research Results

Organic Chemicals: 40

Sulfur Compounds: 82

Thiones: 6

2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester: 2

2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester: 2

Related Diseases

1.	Reperfusion Injury 01/01/2008 - "EXPERIMENTAL APPROACH: This study investigated the pharmacological activity of a new H(2)S-releasing derivative of diclofenac, S-diclofenac (2-[(2,6-dichlorophenyl)amino]benzeneacetic acid 4-(3H-1,2-dithiole-3-thione-5-yl)-phenyl ester) in the isolated rabbit heart submitted to low-flow ischaemia-reperfusion damage" 01/01/2008 - "Perfusion with the nitric oxide (NO) synthase inhibitor N(G)-monomethyl-L-arginine worsened the myocardial ischaemia-reperfusion damage, but this was dose-dependently prevented by S-diclofenac and NaHS, suggesting that the released H(2)S may have overcome NO deficiency" Get all the results and reference details, order at left...
2.	Inflammation 03/01/2007 - "S-diclofenac administration inhibited lipopolysaccharide-induced inflammation (as evidenced by reduced lung and liver myeloperoxidase activity) and caused significantly less gastric toxicity than diclofenac" Get all the results and reference details, order at left...
3.	Contracture 01/01/2008 - "KEY RESULTS: S-diclofenac (3, 10 and 30 microM), despite inhibiting prostacyclin generation by cardiac tissues, achieved dose-dependent normalization of coronary perfusion pressure, reducing left ventricular contracture during ischaemia and improving left ventricular developed pressure and +/-dP/dt(max) at reperfusion" Get all the results and reference details, order at left...
4.	Cardiovascular Diseases (Cardiovascular Disease) 01/01/2008 - "The pharmacological profile of S-diclofenac and its anti-inflammatory activity, with diminished gastrointestinal side effects, offer therapeutic applications in cardiovascular disease." Get all the results and reference details, order at left...
4 Diseases and 2 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Diclofenac (SR 38)
2.	Nitric Oxide Synthase (NO Synthase)
3.	Epoprostenol (Prostacyclin)
4.	Nitric Oxide (Nitrogen Monoxide)
5.	Peroxidase (Myeloperoxidase)
6.	Arginine (L-Arginine)
7.	sodium bisulfide (NaHS)
7 Drugs and Important Bio-Agents and 2 more articles analyzed in the Research Interface, order at left...

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