aildenafil

structure in first source

Also Known As:

1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4 -ethoxyphenyl)sulfonyl)-cis-3,5-dimethylpiperazine; 7H-Pyrazolo(4,3-d)pyrimidin-7-one, 5-(5-(((3R,5S)-3,5-dimethyl-1-piperazinyl)sulfonyl)-2-ethoxyphenyl)-1,4-dihydro-1-methyl-3-propyl-

Networked: 4 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - aildenafil: 4
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Sulfones: 534
    - aildenafil: 4

Experts

1.	Cui, Wan-Shou: 1 article (08/2021)
2.	Feng, Yu-Hong: 1 article (08/2021)
3.	Guan, Rui-Li: 1 article (08/2021)
4.	Lei, Hong-En: 1 article (08/2021)
5.	Liu, Ji-Hong: 1 article (08/2021)
6.	Tian, Long: 1 article (08/2021)
7.	Wang, Jiang: 1 article (08/2021)
8.	Wang, Tao: 1 article (08/2021)
9.	Xin, Zhong-Cheng: 1 article (08/2021)
10.	Yao, Chen: 1 article (08/2021)

Related Diseases

Erectile Dysfunction

08/01/2021 - "Efficacy and safety of aildenafil citrate in Chinese men with erectile dysfunction: a multicenter, randomized, double-blind, placebo-controlled crossover trial."
12/01/2006 - "Integrated analyses were made of 8-week, randomized, double-blind, placebo-controlled phase 2 clinical trials involving 250 men with mild-to-severe erectile dysfunction of various etiologies who received aildenafil citrate 30 or 60 mg (n = 167) or placebo (n = 83). "
08/01/2021 - "To evaluate the efficacy and safety of aildenafil citrate in the treatment of erectile dysfunction (ED) in Chinese population. "
12/01/2006 - "The aildenafil citrate therapy significantly ameliorated erectile function and was well tolerated by a wide range of patients with erectile dysfunction."
06/01/2014 - "Aildenafil, 1-{[3-(6, 7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo [4, 3-d] primidin-5-yl)-4-ethoxyphenyl] sulfonyl}-cis-3, 5-dimethylpiperazine, a phosphodiesterase type V enzyme inhibitor (PDE5I), is under development for treatment of erectile dysfunction (ED). "

Related Drugs and Biologics

1.	Citric Acid (Citrate)
2.	Phosphodiesterase 5 Inhibitors
3.	Type 5 Cyclic Nucleotide Phosphodiesterases
4.	Enzyme Inhibitors (Inhibitors, Enzyme)
5.	Sildenafil Citrate (Viagra)
6.	mutaprodenafil
7.	imidazole

Related Therapies and Procedures

1.	Therapeutics