|1.||Chu, Shu-Chen: 3 articles (01/2014 - 01/2007)|
|2.||Hsieh, Yih-Shou: 3 articles (01/2014 - 01/2007)|
|3.||Awasthi, Sanjay: 2 articles (08/2015 - 04/2011)|
|4.||Singhal, Jyotsana: 2 articles (08/2015 - 04/2011)|
|5.||Singhal, Sharad S: 2 articles (08/2015 - 04/2011)|
|6.||Wu, Kaijie: 2 articles (07/2014 - 03/2014)|
|7.||Fan, Jinhai: 2 articles (07/2014 - 03/2014)|
|8.||Wang, Xinyang: 2 articles (07/2014 - 03/2014)|
|9.||Zhu, Jianning: 2 articles (07/2014 - 03/2014)|
|10.||Ning, Zhongyun: 2 articles (07/2014 - 03/2014)|
08/01/2015 - "According to in vitro and preclinical mouse studies, 2'-hydroxyflavanone can both protect the VHL locus and prevent the progression of VHL-mutant cancer. "
08/01/2015 - "Therefore, the discovery of plant-derived cancer therapies, such as 2'-hydroxyflavanone, offers a new strategy for combating this highly resistant cancer. "
07/01/2014 - "2'-hydroxyflavanone inhibits prostate tumor growth through inactivation of AKT/STAT3 signaling and induction of cell apoptosis."
01/01/2014 - "Furthermore, in vivo experiments showed that 2'-hydroxyflavanone inhibited the tumor growth of 143 B cells. "
06/01/2004 - "The appearance of apoptotic cells with H&E staining, and an increase in p21, but not p53, protein by immunohistochemistry were observed in tumor tissues under 2'-OH flavanone treatment. "
|2.||Osteosarcoma (Osteogenic Sarcoma)
01/01/2014 - "2'-hydroxyflavanone induces apoptosis of human osteosarcoma 143 B cells by activating the extrinsic TRAIL- and intrinsic mitochondria-mediated pathways."
01/01/2014 - "2'-hydroxyflavanone induced the apoptosis of 143 B cells via the extrinsic TRAIL- and intrinsic mitochondrial-dependent pathways, indicating its potential for inducing cancer apoptosis in osteosarcoma. "
01/01/2014 - "Among the 4 flavanones under study, 2'-hydroxyflavanone exhibited the greatest potency to reduce the cell viability of 143 B cells in 4 osteosarcoma cells. "
|3.||Urinary Bladder Neoplasms (Bladder Cancer)
03/01/2014 - "Wound healing assay and Transwell (TM); assay were conducted to study the effect of 2'-hydroxyflavanone on migration and invasion of bladder cancer cells, respectively. "
03/01/2014 - "To study the effect of 2'-hydroxyflavanone on proliferation, invasion and migration of bladder cancer cells and its mechanism. "
03/01/2014 - "2'-hydroxyflavanone can effectively inhibit bladder cancer cell proliferation, invasion and migration, in which the inhibition of AKT/STAT3 signaling pathway may play an important role."
03/01/2014 - "2'-hydroxyflavanone inhibited the proliferation of bladder cancer cells (5637, T24, UMUC-3, 253J) in a time- and dose- dependent manner. "
03/01/2014 - "[Inhibitory effect of 2'-hydroxyflavanone on proliferation, invasion and migration of bladder cancer cells in vitro via blocking AKT/STAT3 signaling pathway]."
|4.||Lewis Lung Carcinoma
01/01/2007 - "Finally, flavanone and 2'-OH flavanone were evidenced by its inhibition on the growth of A549 and Lewis lung carcinoma cells in vivo."
05/01/2007 - "Finally, oral administration of flavanone and 2'-OH flavanone were evidenced by its inhibition on the metastasis of A549 cells and Lewis lung carcinoma (LLC) cells in vivo. "
|5.||Prostatic Neoplasms (Prostate Cancer)
10/01/2013 - "2'-Hydroxyflavanone not only inhibited proliferation of prostate cancer cells, but also repressed androgen-responsiveness, suggesting that it might be a useful agent in preventing recurrence of prostate cancer."
10/01/2013 - "To investigate the effect of 2'-hydroxyflavanone on proliferation, prostate cancer cells were treated with 2'-hydroxyflavanone. "
10/01/2013 - "We explored the effect of 2'-hydroxyflavanone on proliferation and androgen responsiveness using prostate cancer cell lines. "
07/01/2014 - "2'-Hydroxyflavanone (2HF), a nontoxic natural flavonoid, has been shown to exhibit pleiotropic anticancer effects in many cancer types, including prostate cancer (PCa). "
10/01/2013 - "Repression of cell proliferation and androgen receptor activity in prostate cancer cells by 2'-hydroxyflavanone."
|5.||Prostaglandins E (PGE)
|7.||Caspase 3 (Caspase-3)
|8.||Cytochromes c (Cytochrome c)
|2.||Drug Therapy (Chemotherapy)