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cloxyquin

has antitubercular activity; structure in first source

Also Known As:

5-chloroquinolin-8-ol

Networked: 6 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Hydroxyquinolines: 9
        Oxyquinoline: 287
        Chloroquinolinols
        cloxyquin: 6

Experts

1.	Brabec, Viktor: 1 article (01/2022)
2.	Dilek, Mustafa: 1 article (01/2022)
3.	Duzcu, Selma Erdogan: 1 article (01/2022)
4.	Hreusova, Monika: 1 article (01/2022)
5.	Kasparkova, Jana: 1 article (01/2022)
6.	Kilinc, Erkan: 1 article (01/2022)
7.	Kilinc, Yasemin Baranoglu: 1 article (01/2022)
8.	Kostrhunova, Hana: 1 article (01/2022)
9.	Markova, Lenka: 1 article (01/2022)
10.	Novohradsky, Vojtech: 1 article (01/2022)

Related Diseases

1.	Brain Injuries (Brain Injury) 01/01/2022 - "Three different doses of cloxyquin (0.2, 1 and 5 mg/kg) were studied in ibotenate-induced perinatal brain injury (PBI) in P5 rat-pups. " 01/01/2022 - "Cloxyquin dose-dependently exerted protective effects against excitotoxic-induced neonatal brain injury and neuroinflammation. " 01/01/2022 - "Activation of TRESK background potassium channels by cloxyquin exerts protective effects against excitotoxic-induced brain injury and neuroinflammation in neonatal rats." 01/01/2022 - "We investigated effects of activation of TRESK channels by selective activator cloxyquin on excitotoxic-induced brain injury and neuroinflammation involving brain mast cells and inflammatory cytokines in neonatal rats. "
2.	Neuroinflammatory Diseases 01/01/2022 - "Cloxyquin dose-dependently exerted protective effects against excitotoxic-induced neonatal brain injury and neuroinflammation. " 01/01/2022 - "Activation of TRESK background potassium channels by cloxyquin exerts protective effects against excitotoxic-induced brain injury and neuroinflammation in neonatal rats." 01/01/2022 - "We investigated effects of activation of TRESK channels by selective activator cloxyquin on excitotoxic-induced brain injury and neuroinflammation involving brain mast cells and inflammatory cytokines in neonatal rats. "
3.	Pain (Aches) 12/30/2019 - "Cloxyquin is a potential therapeutic compound possessing various bioactivities, especially antibacterial, antifungal, cardioprotective, and pain relief activities. " 12/01/2019 - "We then demonstrate the importance of TRESK to pain states by showing that the TRESK activator, cloxyquin, can reduce the spontaneous firing of nociceptors in an in vitro human pain model. "
4.	Rhabdomyosarcoma 01/01/2022 - "In this work, gallium(III) complex with cloxyquin (5-chloro-8-quinolinol, HClQ) ligands is shown to effectively inhibit proliferation of rhabdomyosarcoma cells, the frequent, aggressive, and poorly treatable cancer of children. " 01/01/2022 - "Gallium(III) Complex with Cloxyquin Ligands Induces Ferroptosis in Cancer Cells and Is a Potent Agent against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells."
5.	Neoplasms (Cancer) 01/01/2022 - "In this work, gallium(III) complex with cloxyquin (5-chloro-8-quinolinol, HClQ) ligands is shown to effectively inhibit proliferation of rhabdomyosarcoma cells, the frequent, aggressive, and poorly treatable cancer of children. " 01/01/2022 - "Gallium(III) Complex with Cloxyquin Ligands Induces Ferroptosis in Cancer Cells and Is a Potent Agent against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells."

Related Drugs and Biologics

1.	Tandem Pore Domain Potassium Channels (Tandem Pore Domain Potassium Channel)
2.	Cytokines
3.	Ligands
4.	Gallium