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(meso- tetrakis(4- sulfonatophenyl)porphyrinato)oxovanadium(IV)(4- )

has antidiabetic activity; structure in first source

Also Known As:

VO(tpps)

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Coordination Complexes: 576
  - Metalloporphyrins: 178
    - (meso-tetrakis(4-sulfonatophenyl)porphyrinato)oxovanadium(IV)(4-): 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - Tetrapyrroles: 70
        Porphyrins: 3316
        Metalloporphyrins: 178
        (meso-tetrakis(4-sulfonatophenyl)porphyrinato)oxovanadium(IV)(4-): 1
- Fused-Ring Heterocyclic Compounds
  - 4 or More Rings Heterocyclic Compounds
    - Tetrapyrroles: 70
      - Porphyrins: 3316
        Metalloporphyrins: 178
        (meso-tetrakis(4-sulfonatophenyl)porphyrinato)oxovanadium(IV)(4-): 1
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Tetrapyrroles: 70
    - Porphyrins: 3316
      - Metalloporphyrins: 178
        (meso-tetrakis(4-sulfonatophenyl)porphyrinato)oxovanadium(IV)(4-): 1
Biological Factors: 2472
- Biological Pigments: 1
  - Porphyrins: 3316
    - Metalloporphyrins: 178
      - (meso-tetrakis(4-sulfonatophenyl)porphyrinato)oxovanadium(IV)(4-): 1

Experts

1.	Saha, Tapan Kumar: 1 article (03/2007)
2.	Sakurai, Hiromu: 1 article (03/2007)
3.	Yoshikawa, Yutaka: 1 article (03/2007)

Related Diseases

1.	Metabolic Syndrome (Dysmetabolic Syndrome X) 03/01/2007 - "Based on these observations, VO(tpps) is proposed to be an orally active oxovanadium(IV)-porphyrin complex for treating not only type 2 diabetes but also metabolic syndromes in animals." 03/01/2007 - "In addition, metabolic syndromes characterized by insulin and leptin resistance were significantly improved in VO(tpps)-treated KKA(y) mice compared with those treated with VS. The improvement in diabetes was validated by oral glucose tolerance test and decrease in HbA(1c) concentration. "
2.	Type 2 Diabetes Mellitus (MODY) 03/01/2007 - "Based on these observations, VO(tpps) is proposed to be an orally active oxovanadium(IV)-porphyrin complex for treating not only type 2 diabetes but also metabolic syndromes in animals."

Related Drugs and Biologics

1.	Leptin
2.	Insulin (Novolin)
3.	Glucose (Dextrose)
4.	Porphyrins
5.	oxovanadium IV